27085-71-8

Upstream product

• 14546-70-4 3-(3,4,5-trimethoxy-phenyl)-oxiranecarboxylic acid methyl ester 
• 137-07-5 2-amino-benzenethiol 

Downstream Products

• 47729-17-9 3c-acetoxy-5-(2-dimethylamino-ethyl)-2r-(3,4,5-trimethoxy-phenyl)-2,3-dihydro-5H-benzo[b][1,4]thiazepin-4-one 

Relevant academic research and scientific papers

Solid phase synthesis of hydroxy benzothiazepinones through cyclative release under thermolysis

Hydroxy benzothiazepinones were synthesized by a simple procedure involving epoxidation of polymer bound cinnamic acids followed by nucleophilic opening of the resulting glycidic ester by o-aminothiophenol to afford the intermediate hydroxy anilino-esters which underwent cyclization cleavage on heating in DMF to release the product completely.