27089-56-1 Usage
General Description
2-Thio-6-azauridine is a synthetic, sulfur-containing pyrimidine analogue known for its potential antineoplastic activity. It works by inhibiting enzymes involved in pyrimidine biosynthesis, which eventually prevents the synthesis of DNA and RNA in cells. This inhibition is believed to suppress cell proliferation, making 2-thio-6-azauridine a significant candidate in cancer treatment research. However, like many chemotherapy agents, this chemical can have toxic side effects, making dosage and administration critical factors to be considered during treatment.
Check Digit Verification of cas no
The CAS Registry Mumber 27089-56-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,0,8 and 9 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 27089-56:
(7*2)+(6*7)+(5*0)+(4*8)+(3*9)+(2*5)+(1*6)=131
131 % 10 = 1
So 27089-56-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H11N3O5S/c12-2-3-5(14)6(15)7(16-3)11-8(17)10-4(13)1-9-11/h1,3,5-7,12,14-15H,2H2,(H,10,13,17)/t3-,5-,6-,7-/m1/s1
27089-56-1Relevant articles and documents
Process for preparing 2-thiouracil nucleosides
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, (2008/06/13)
Some new 1-(2- or 3-deoxy-β-D-pentofuranosyl)-2-thiouracils and 1-β-D-pentofuranosyl-2-thio-6-azauracils have been prepared. Further, it has been found that the known nucleoside compound, 1-β-D-ribofuranosyl-2-thiouracil is active against Herpes virus and against L-1210 leukemia in mice. An improved method of preparing corresponding 2-0-methyluracil and 2-0-methyl-6-azauracil intermediates is described. The method preserves the β-configuration of the starting nucleoside.
