27123-33-7

Basic information

• Product Name: 20-nor-β,β-carotene
• CAS NO: 27123-33-7
• Molecular Weight: 522.858
• Mol File: 27123-33-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 20-nor-β,β-carotene(CAS DataBase Reference)
• NIST Chemistry Reference: 20-nor-β,β-carotene(27123-33-7)
• EPA Substance Registry System: 20-nor-β,β-carotene(27123-33-7)

Safety Data

• Hazardous Substances Data: 27123-33-7(Hazardous Substances Data)

Upstream product

• 53282-28-3 [(2E,4E)-3-methyl-5-(2,6,6-trimethylcyclohex-1-en-1-yl)penta-2,4-dienyl]triphenylphosphonium chloride 

Relevant articles and documents

The substrate specificity of β,β-carotene 15,15′-monooxygenase

The synthesis of several substrate analogues of the enzyme β,β-carotene 15,15′-monooxygenase is reported. The substrate specificity of enriched enzyme fractions isolated from chicken intestinal mucosa was investigated. Regarding substrate binding/cleavage, these experiments demonstrate that i) any deviation from the rod-like β,β-carotene structure is not tolerated, ii) one 'natural', unsubstituted β-ionone ring is required, iii) the position and presence of the Me groups attached to the polyene chain is significant. These results suggest a hydrophobic barrel-like substrate binding site in which the protein's amino acid residues through interaction with the Me groups, direct the central C=C bond in binding distance to the active site's metal-oxo center, supporting the unique regiospecificity of cleavage to retinal (provitamin A).