271245-15-9

Upstream product

• 271245-14-8 thexyldimethylsilyl O-(methyl 3-O-benzoyl-4,5:7,8-di-O-isopropylidene-α-D-glycero-D-talo-2-octulopyranosonate)-(2->6)-2-azido-3,4-di-O-benzyl-2-deoxy-β-D-glucopyranoside 

Downstream Products

• 271245-16-0 thexyldimethylsilyl O-(methyl 4,5:7,8-di-O-isopropylidene-3-O-thiobenzoyl-α-D-glycero-D-talo-2-octulopyranosonate)-(2->6)-2-azido-3,4-di-O-benzyl-2-deoxy-β-D-glucopyranoside 
• 271245-19-3 thexyldimethylsilyl O-(methyl 3-O-acetyl-4,5:7,8-di-O-isopropylidene-α-D-glycero-D-talo-2-octulopyranosonate)-(2->6)-2-acetamido-3,4-di-O-benzyl-2-deoxy-β-D-glucopyranoside 
• 271245-17-1 thexyldimethylsilyl O-(methyl 3-deoxy-4,5:7,8-di-O-isopropylidene-α-D-manno-2-octulopyranosonate)-(2->6)-2-acetamido-3,4-di-O-benzyl-2-deoxy-β-D-glucopyranoside 

Relevant academic research and scientific papers

Synthesis of 3-deoxy-D-manno-2-octulosonic acid (Kdo) and D-glycero-D-talo-2-octulosonic acid (Ko) and their α-glycosides

Reaction of 2,3:5,6-di-O-isopropylidene-D-mannofuranose 1 with C-2 lithio derivatives of glyoxylate mercaptal in the presence of MgBr2 afforded D-glycero-D-galacto-2-octulosonates 2 and 3, respectively. Their 3-O-deoxygenation led to Kdo. N-Iod