27143-09-5

Basic information

• Product Name: ETHYL (2E)-CHLORO[(4-CHLOROPHENYL)HYDRAZONO]ACETATE
• Synonyms: ETHYL 2-CHLORO-2-[2-(4-CHLOROPHENYL)HYDRAZONO]-ACETATE;ETHYL (2E)-CHLORO[(4-CHLOROPHENYL)HYDRAZONO]ACETATE;Ethyl 2-chloro-2-[2-(4-chlorophenyl)hydrazono]-;Acetic acid, 2-chloro-2-[2-(4-chlorophenyl)hydrazinylidene]-, ethyl ester;ethyl (Z)-2-chloro-2-(2-(4-chlorophenyl)hydrazono)acetate;(Z)-Ethyl 2-chloro-2-(2-(4-chlorophenyl)hydrazono)acetate;Apixaban Impurity R
• CAS NO: 27143-09-5
• Molecular Formula: C₁₀H₁₀Cl₂N₂O₂
• Molecular Weight: 261.1
• EINECS: 1308068-626-2
• Mol File: 27143-09-5.mol
• Article Data: 15

Chemical Properties

• Melting Point: 150 °C
• Boiling Point: 337.1 °C at 760 mmHg
• Flash Point: 157.7 °C
• Appearance: /
• Density: 1.33 g/cm³
• Vapor Pressure: 0.000107mmHg at 25°C
• Refractive Index: 1.56
• Storage Temp.: -20°C Freezer, Under inert atmosphere
• Solubility: DMSO (Slightly), Methanol (Slightly)
• PKA: 11.04±0.10(Predicted)
• CAS DataBase Reference: ETHYL (2E)-CHLORO[(4-CHLOROPHENYL)HYDRAZONO]ACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL (2E)-CHLORO[(4-CHLOROPHENYL)HYDRAZONO]ACETATE(27143-09-5)
• EPA Substance Registry System: ETHYL (2E)-CHLORO[(4-CHLOROPHENYL)HYDRAZONO]ACETATE(27143-09-5)

Safety Data

• Hazardous Substances Data: 27143-09-5(Hazardous Substances Data)

Usage

Uses

(Z)?-?Ethyl 2-?chloro-?2-?(2-?(4-?chlorophenyl)?hydrazono)?acetate is a reagent used in the preparation of pyrimidine and pyrimidinone-based compounds for their use as antimicrobials.

InChI:InChI=1/C10H10Cl2N2O2/c1-2-16-10(15)9(12)14-13-8-5-3-7(11)4-6-8/h3-6,13H,2H2,1H3/b14-9+

Upstream product

• 106-47-8 4-chloro-aniline 
• 609-15-4 ethyl 2-chloro-3-oxo-butyrate 
• 2028-74-2 p-chlorobenzenediazonium chloride 
• 105-39-5 chloroacetic acid ethyl ester 
• 7782-50-5 chlorine 
• 10475-63-5 3-oxo-2-(phenylhydrazono)butyric acid ethyl ester 
• 7791-25-5 sulfuryl dichloride 
• 127-09-3 sodium acetate 
• 18794-97-3 ethyl 2-(4-chlorophenylhydrazono)-3-oxobutyrate 
• 623-73-4 diazoacetic acid ethyl ester 
• 17333-85-6 4-chlorophenyldiazonium salt 

Downstream Products

• 56462-76-1 amino-(4-chloro-phenylhydrazono)-acetic acid ethyl ester 
• 56885-93-9 4-(4-chloro-phenyl)-5-(2-oxo-2-phenyl-ethylidene)-4,5-dihydro-[1,3,4]thiadiazole-2-carboxylic acid ethyl ester 
• 144309-71-7 (4S,5R)-4-Benzo[1,3]dioxol-5-yl-1-(4-chloro-phenyl)-5-(4-methoxy-benzoyl)-4,5-dihydro-1H-pyrazole-3-carboxylic acid ethyl ester 
• 117620-66-3 1-(4-Chloro-phenyl)-5-cyano-4,5-dihydro-1H-pyrazole-3-carboxylic acid ethyl ester 
• 64989-61-3 [1-(4-chloro-phenyl)-4-phenyl-1H-pyrazol-3-yl]-methanol 
• 64989-58-8 [1-(4-chloro-phenyl)-4-phenyl-1H-pyrazol-3-yl]-acetonitrile 
• 64989-59-9 [1-(4-chloro-phenyl)-4-phenyl-1H-pyrazol-3-yl]-acetic acid 
• 64989-60-2 ethyl 1-(4-chlorophenyl)-4-phenyl-1H-pyrazole-3-carboxylate 
• 64989-62-4 3-bromomethyl-1-(4-chloro-phenyl)-4-phenyl-1H-pyrazole 
• 908584-68-9 ethyl 5-amino-1(4-chlorophenyl)-4-cyano-1H-pyrazole-3-carboxylate 
• 1255761-93-3 ethyl 3-(4-chlorophenyl)-7-phenyl-3H-pyrrolo[2,3-e][1,2,4]triazolo[4,3-a]pyrazine-1-carboxylate 
• 1255761-90-0 ethyl 3-(p-chlorophenyl)-7-phenyl-5,6-dihydro-3H-pyrrolo[2,3-e][1,2,4]triazolo[4,3-a]pyrazine-1-carboxylate 
• 1255761-88-6 1,11-bis-(4-chlorophenyl)-3,9-diethoxycarbonyl-6-phenyl-[1,11,11a,11b-tetrahydrobis[1,2,4]triazolo[3,4-c:4',3'-a]-3H-pyrrolo[2,3-e]pyrazine] 
• 1255761-95-5 3-(4-chlorophenyl)-6-[ethoxy-N-(4-chlorophenyl)-2-oxoethanehydrazonyl]-7-phenyl-5,6-dihydro-3H-pyrrolo[2,3-e][1,2,4]triazolo[4,3-a]pyrazine-1-carboxylate 

Relevant articles and documents

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