27150-91-0Relevant academic research and scientific papers
1-Iodomethyl-3,4-diphenyl-2,6-dioxabicyclo[2.2.0]hexane: The first example of a [2.2.0] fused ketal
Wang, Gan,Wang, Ying,Arcari, Joel T.,Howell, Amy R.,Rheingold, Arnold L.,Concolino, Thomas
, p. 7051 - 7053 (1999)
The preparation of 1-iodomethyl-3,4-diphenyl-2,6- dioxabicyclo[2.2.0]hexane (12) is described. This represents the first reported example of a [2.2.0] fused ketal. The key step involved the iodoetherification of a 2-methyleneoxetane 11 containing a pendan
THE REACTION OF SMALL RING COMPOUND WITH CARBON MONOXIDE. THE CARBONYLATION OF OXIRANE
Kamiya, Yoshio,Kawato, Katsuhito,Ohta, Hiroyuki
, p. 1549 - 1552 (1980)
The carbonylation of oxiranes catalyzed by rhodium complex afforded β-lactones.Various factors which control the above reaction are presented.
HETEROCYCLYL-SUBSTITUTED OXETANES FOR THE TREATMENT OF PROLIFERATIVE OR INFECTIOUS DISEASES
-
Page/Page column 28, (2008/06/13)
Oxetane-containing nucleosides, particularly non-reducing psiconucleoside oxetanes (1) are described herein. Therapeutic application of these oxetane compounds toward the treatment of nucleoside analog related disorders such as disorders involving cellular proliferation and infection are also described.
Enzymatic kinetic resolution of tropic acid
Klomp, Dirk,Peters, Joop A.,Hanefeld, Ulf
, p. 3892 - 3896 (2007/10/03)
A new strategy has been developed for the CAL-B catalysed kinetic resolution of tropic acid by which both enantiomers of tropic acid can be obtained in good enantiomeric excess. (R)-Tropic acid was synthesised with 90% ee and (S)-tropic acid butyl ester in 99% ee by the hydrolysis of tropic acid butyl ester. The other enantiomers were available through the enzymatically catalysed reaction of tropic acid lactone with butanol to give (S)-tropic acid lactone and (R)-tropic acid ester in >98% ee.
