2716-13-4Relevant academic research and scientific papers
Scandium-Catalyzed para-Selective Alkylation of Aromatic Amines with Alkenes
Su, Jianhong,Cai, Yanping,Xu, Xin
, p. 9055 - 9059 (2019)
An efficient para-alkylation of primary and secondary anilines with a variety of sterically encumbered alkenes using a simple β-diketiminato scandium catalyst is reported. This protocol features 100% atom economy, excellent chemo- and regioselectivity, broad substrate scope, and good functional group tolerance. Mechanistic studies disclosed that the reaction probably proceeded via a tandem hydroamination/Hofmann-Martius rearrangement.
