27163-17-3

Upstream product

• 463-71-8 thiophosgene 
• 108272-17-9 N-acetyl-4,4'-diaminodiphenylamine 
• 60516-11-2 4-Acetamido-4'-nitrodiphenylamine 
• 6149-34-4 N-(4-nitrophenyl)-1,4-phenylenediamine 

Relevant academic research and scientific papers

Synthesis of Potential Metabolites of 4-Methyl-1-piperazine

4-Methyl-1-piperazine (1) is an experimental antifilarial drug.In order to investigate its metabolic fate in laboratory animals and also man several potential metabolites, arising from general metabolic conversions of 1, viz.N-oxidation (8), N-demethylation and acetylation (11) and (12), desulphuration (15), nitro group reduction to aryl amino (16) and further acetylation to arylacetamido (17), have been synthesized for identification/quantitation purposes.