2718-35-6

Upstream product

• 110-91-8 morpholine 
• 2651-14-1 Dimethyl N-(4-Aminophenylsulphonyl)dithiocarbonimidate 
• 2651-13-0 p-acetylaminobenzenesulphonyliminodithiocarbonic acid dimethyl ester 
• 121-61-9 p-acetylaminobenzenesulfonamide 
• 2651-20-9 N-(4-acetylamino-benzenesulfonyl)-morpholine-4-carboximidothioic acid methyl ester 

Relevant academic research and scientific papers

Synthesis and bactericidal activity of some symmetrical bisthioalkyl derivatives

The paper deals with the synthesis of some bactericides.The dithioacetal required are obtained by the reaction of active methylene compounds and aryl sulphonamides with carbon disulphide in alkaline conditions and subsequent alkylation with dimethyl sulphate.These compounds are then reacted with various pharmacopohores.All the compounds show moderate to significant activity with few compounds showing very high broad spectrum activity.

Syhthesis of N4-substituted sulphanilamides and evaluation of their antibacterial efficacy

Pharmacologically active compounds belonging to the classes of p-thiocyano and p-aminobenzene sulphonamides have been synthesised and their antimicrobial activity evaluated against Gram + ve and Gram - ve bacteria.The compounds of both the classes show more inhibition of Gram -ve bacteria as compared to Gram + ve.