27180-91-2

Basic information

• Product Name: 3-(3-ethylhexahydro<1H>azepine-3-yl)phenol hydrobromide
• CAS NO: 27180-91-2
• Molecular Weight: 300.239
• Mol File: 27180-91-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-(3-ethylhexahydro<1H>azepine-3-yl)phenol hydrobromide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3-ethylhexahydro<1H>azepine-3-yl)phenol hydrobromide(27180-91-2)
• EPA Substance Registry System: 3-(3-ethylhexahydro<1H>azepine-3-yl)phenol hydrobromide(27180-91-2)

Safety Data

• Hazardous Substances Data: 27180-91-2(Hazardous Substances Data)

Upstream product

• 114879-92-4 3-ethylhexahydro-3-(3-methoxyphenyl)<1H>azepine hydrobromide 
• 52956-27-1 1-(3-methoxyphenyl)propanol 
• 68266-31-9 1-chloro-1-(3-methoxyphenyl)propane 
• 1611-75-2 2-(3-methoxyphenyl)butyronitrile 
• 343227-97-4 methyl 5-(aminomethyl)-5-(3-methoxyphenyl)heptanoate 
• 76798-14-6 methyl 5-cyano-5-(3-methoxyphenyl)heptanoate 
• 591-31-1 3-methoxy-benzaldehyde 
• 27185-01-9 3-Ethyl-3-(3-hydroxy-phenyl)-azepane-1-carboxylic acid ethyl ester 

Relevant articles and documents

NOVEL CARBAMATE AMINO ACID AND PEPTIDE PRODRUGS OF OPIOIDS AND USES THEREOF

Carbamate linked prodrugs of meptazinol and other opioid analgesics are provided. The prodrug moiety may comprise a single amino acid or short peptide. Additionally, the present invention relates to methods for reducing gastrointestinal side effects in a subject, the gastrointestinal side effects being associated with the administration of an opioid analgesic. The methods comprise orally administering an opioid prodrug or pharmaceutically acceptable salt thereof to a subject, wherein the opioid prodrug is comprised of an opioid analgesic covalently bonded through a carbamate linkage to a prodrug moiety, and wherein upon oral administration, the prodrug or pharmaceutically acceptable salt minimizes at least one gastrointestinal side effect associated with oral administration of the opioid analgesic alone. Compositions for use with the method are also provided.