27187-47-9Relevant academic research and scientific papers
An Improved Method for γ-Carboxylation of β-Diketones. Synthesis of 4-Alkyl-3,5-dioxohexanoic Acids and 5-Alkyl Derivatives of Triacetic Acid Lactone
Cervello, Jordi,Marquet, Jorge,Moreno-Manas, Marcial
, p. 1931 - 1941 (2007/10/02)
γ-Carboxylation of β-diketones, 1, can be improved using samples containing 100percent of ketoenol tautomers, 3, prepared by mild hydrolysis of the corresponding copper(II) complexes 2.Cyclization of the so formed 4-alkyl-3,5-dioxohexanoic acids, 4, affords 5-alkyl-4-hydroxy-6-methyl-2-pyrones, 5.
