27188-93-8Relevant academic research and scientific papers
Efficient access to C1- and C3-functionalized isoquinolines: Towards potential lanthanide ligands
Caille, Fabien,Buron, Frederic,Toth, Eva,Suzenet, Franck
experimental part, p. 2120 - 2127 (2011/05/09)
Highly substituted isoquinolines have been synthesized by two different pathways using either a Pictet-Grams or a Bischler-Napieralski approach. While the first synthesis afforded C1-functionalizable 1,3-dimethylisoquinoline derivatives, the second approa
Cycloaddition d'ylures d'azomethine derives de la 3,4-dihydro-6,7-dimethoxy-3-methoxycarbonyl-isoquinoleine
Lakhlifi, Tahar,Sedqui, Ahmed,Laude, Bernard,An, Nguyen Dinh,Vebrel, Joel
, p. 1156 - 1160 (2007/10/02)
Three azomethine ylide precursors including the 3,4-dihydro-6,7-dimethoxyisoquinoline-3-carboxylate moiety were synthesized.The 1,3-dipolar species formed from these products react with activated dipolarophilic olefines leading diastereospecifically to derivatives of 4',5'-dimethoxy-1,2-benzo-4,7-imino-4-methoxycarbonyl-1-cycloheptene.Proton magnetic resonance data allowed the determination of the stereochemistry of the cycloadducts. Key words: cyclic azomethine ylide, azabicyclic compounds, stereochemistry.
