272-16-2 Usage
Uses
Used in Organic Synthesis:
9-thia-8-azabicyclo[4.3.0]nona-1,3,5,7-tetraene is utilized as a key intermediate in organic synthesis for the development of novel compounds with unique properties. Its complex structure and reactivity make it a valuable building block for creating new molecules with potential applications in various industries.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 9-thia-8-azabicyclo[4.3.0]nona-1,3,5,7-tetraene is employed as a potential pharmaceutical candidate due to its unique molecular structure. Its sulfur and nitrogen-containing groups, along with its high degree of unsaturation, may contribute to the development of new drugs with improved therapeutic effects and selectivity.
Used in Material Science:
9-thia-8-azabicyclo[4.3.0]nona-1,3,5,7-tetraene is also used in material science for the design and synthesis of advanced materials with specific properties. Its complex structure and reactivity can be harnessed to create materials with unique characteristics, such as enhanced stability, conductivity, or optical properties, which can be applied in various technological applications.
Used in Research and Development:
Due to its unusual structure and potential applications, 9-thia-8-azabicyclo[4.3.0]nona-1,3,5,7-tetraene is extensively used in research and development to explore its properties and potential uses. Further studies on 9-thia-8-azabicyclo[4.3.0]nona-1,3,5,7-tetraene can provide valuable insights into its behavior, reactivity, and possible applications in different fields, paving the way for new discoveries and innovations.
Check Digit Verification of cas no
The CAS Registry Mumber 272-16-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 2,7 and 2 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 272-16:
(5*2)+(4*7)+(3*2)+(2*1)+(1*6)=52
52 % 10 = 2
So 272-16-2 is a valid CAS Registry Number.
InChI:InChI=1/C7H5NS/c1-2-4-7-6(3-1)5-8-9-7/h1-5H
272-16-2Relevant academic research and scientific papers
Gas-phase cyclisation reactions of 1-(2-arylthiophenyl)alkaniminyl and 2-(aryliminomethyl)thiophenoxyl radicals
Creed,Leardini,McNab,Nanni,Nicolson,Reed
, p. 1079 - 1085 (2007/10/03)
Flash vacuum pyrolysis (FVP) of the oxime ethers 12-14 and of the sulfides 18-20 at 650°C (10-2-10-3 Torr) gave products derived from the corresponding iminyl and thiophenoxyl radicals. In all cases, benz[d]isothiazoles (e.g., 26) are formed as major products via SHi mechanisms though the yields are greatest with the iminyl precursors. Alternative pathways observed from the thiophenoxyls in specific cases include the formation of the anilinobenzothiophene 36 and of dibenzothiophene 23, via an SHi process and a spirodienyl rearrangement, respectively. There is no evidence for signicant interconversion of the iminyl and thiophenoxyl species.
THERMAL FISSION OF HYDROXYLAMINE DERIVATIVES WITH NEIGHBOURING-GROUP-PARTICIPATION BY THIOETHER FUNCTIONS: PREPARATION OF 1,2-BENZISOTHIAZOLES
Lawson, Alexander J.
, p. 357 - 368 (2007/10/02)
Some of the factors influencing the preparation of 1,2-benzisothiazoles from 2-(alkylthio)phenyl-substituted oximes are discussed.Good yields of 3-aryl-1,2-benzisothiazoles 4 may be obtained from readily available precursors.Reaction takes place under particularly mild conditions when a t-butylthio function is situated anti to the leaving group at oxime-nitrogen and S-N overlap is not restricted by ring-strain in the transition-state.The corresponding N-methyl-hydroxamic acid derivatives 2 give good yields of 2-methyl-1,2-benzisothiazol-3(2H)-one 13 only when a t-butylthio substituent is present, e.g. in 2f.The ethylthio- and i-propylthio-analogues 2d and 2e give the vinylthioethers 12, while the methylthio derivatives 2a-c undergo a novel rearrangement to "Pummerer" esters.The preparation of the polycyclic compounds fluoreno-1,2 thiazole 7 and 2,2'-bi(2H-fluoreno-1,3-thiazine) 8 is described.
