272122-45-9

Usage

Uses

Used in Perfume and Fragrance Industry:
2,6-Octadien-1-ol, 3,7-dimethyl-8-(phenylamino)-, (2E,6E)is used as a fragrance ingredient for its floral and fruity scent, contributing to the creation of various perfumes and fragrances. Its unique aroma profile makes it a valuable addition to the formulations of these products.
Used in Food Industry:
In the food industry, 2,6-Octadien-1-ol, 3,7-dimethyl-8-(phenylamino)-, (2E,6E)is used as a flavoring agent to enhance the taste and aroma of food products. Its ability to impart a pleasant and natural flavor makes it a sought-after ingredient in the development of various food items.
Used in Pest Control:
2,6-Octadien-1-ol, 3,7-dimethyl-8-(phenylamino)-, (2E,6E)is used as an insecticide for its insecticidal properties, making it effective in controlling pests. Its application in pest control helps protect crops and maintain the health of plants, contributing to a more sustainable agricultural practice.
Safety Precautions:
It is important to handle 2,6-Octadien-1-ol, 3,7-dimethyl-8-(phenylamino)-, (2E,6E)with care, as it can be harmful if ingested or inhaled, and may cause irritation to the skin and eyes. Proper safety measures should be taken to minimize the risk of exposure and ensure the safe use of 2,6-Octadien-1-ol, 3,7-dimethyl-8-(phenylamino)-, (2E,6E)- in various applications.

Downstream Products

• 679393-90-9 [1-((2E,6E)-3,7-Dimethyl-8-phenylamino-octa-2,6-dienyloxycarbamoyl)-propyl]-phosphonic acid diethyl ester 
• 679393-86-3 [((2E,6E)-3,7-Dimethyl-8-phenylamino-octa-2,6-dienyloxycarbamoyl)-methyl]-phosphonic acid diethyl ester 
• 788156-83-2 [1-((2E,6E)-3,7-Dimethyl-8-phenylamino-octa-2,6-dienyloxycarbamoyl)-propyl]-phosphonic acid 
• 755752-87-5 [((2E,6E)-3,7-Dimethyl-8-phenylamino-octa-2,6-dienyloxycarbamoyl)-methyl]-phosphonic acid 
• 679393-84-1 O-((2E,6E)-3,7-Dimethyl-8-phenylamino-octa-2,6-dienyl)-hydroxylamine 
• 679393-82-9 2-((2E,6E)-3,7-Dimethyl-8-phenylamino-octa-2,6-dienyloxy)-isoindole-1,3-dione 

Relevant academic research and scientific papers

Design and synthesis of a transferable farnesyl pyrophosphate analogue to Ras by protein farnesyltransferase

The posttranslational addition of a farnesyl moiety to the Ras oncoprotein is essential for its membrane localization and is required for both its biological activity and ability to induce malignant transformation. We describe the design and synthesis of a farnesyl pyrophosphate (FPP) analogue, 8-anilinogeranyl pyrophosphate 3 (AGPP), in which the ω-terminal isoprene unit of the farnesyl group has been replaced with an aniline functionality. The key steps in the synthesis are the reductive amination of the α,β-unsaturated aldehyde 5 to form the lipid analogue 6, and the subsequent conversion of the allylic alcohol 7 to the chloride 8 via Ph3PCl2 followed by displacement with [(n-Bu)4N]3-HP2O7 to give AGPP (3). AGPP is a substrate for protein farnesyltransferase (FTase) and is transferred to Ras by FTase with the same kinetics as the natural substrate, FPP. AGPP is highly selective, showing little inhibitory activity against either geranylgeranyl-protein transferase type I (GGTase I) (K(i) = 0.06 μM, IC50 = 20 μM) or squalene synthase (IC50 = 1000 μM). AGPP is the first efficiently transferable analogue of FPP to be modified at the ω-terminus that provides a platform from which additional analogues can be made to probe the biological function of protein farnesylation. AGPP is the first example of a class of compounds that are alternate substrates for protein isoprenylation that are not inhibitors of squalene synthase.