27221-40-5 Usage
Uses
Used in Research and Laboratory Applications:
1,3-Dimethoxyacridin-9(10H)-one is used as a fluorescent dye for staining nucleic acids and proteins in biological samples, facilitating the visualization and analysis of these biomolecules.
Used in Pharmaceutical Research:
1,3-Dimethoxyacridin-9(10H)-one is used as a potential anti-cancer agent, targeting the inhibition of enzymes that play a role in the growth of cancer cells, thereby offering a novel approach to cancer treatment.
Used in Sensor and Optoelectronic Device Development:
1,3-Dimethoxyacridin-9(10H)-one is used in the development of chemical sensors and optoelectronic devices, capitalizing on its light-emitting properties when stimulated with UV radiation, which can be harnessed for various technological applications.
Check Digit Verification of cas no
The CAS Registry Mumber 27221-40-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,2,2 and 1 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 27221-40:
(7*2)+(6*7)+(5*2)+(4*2)+(3*1)+(2*4)+(1*0)=85
85 % 10 = 5
So 27221-40-5 is a valid CAS Registry Number.
InChI:InChI=1/C15H13NO3/c1-18-9-7-12-14(13(8-9)19-2)15(17)10-5-3-4-6-11(10)16-12/h3-8H,1-2H3,(H,16,17)
27221-40-5Relevant academic research and scientific papers
Acridone derivatives: Design, synthesis, and inhibition of breast cancer resistance protein ABCG2
Boumendjel, Ahcene,Macalou, Sira,Ahmed-Belkacem, Abdelhakim,Blanc, Madeleine,Di Pietro, Attilio
, p. 2892 - 2897 (2007/10/03)
The breast cancer resistance protein (BCRP, ABCG2) is among the latest discovered ABC proteins to be involved in MDR phenotype and for which only few inhibitors are known. In continuing our program aimed at discovering efficient multidrug resistance modul
A Short Efficient Route to Acronycine and Other Acridones
Horne, Stephen,Rodrigo, Russell
, p. 1046 - 1048 (2007/10/02)
A Fries type rearrangement of N-tosyl-o-iodobenzanilides, triggered by lithium-iodine exchange at low temperature is the key step in a general, regiospecific synthesis of acridones.
