27223-35-4 Usage
Uses
Used in Pharmaceutical Industry:
Ketazolam is used as a psychotropic medication for its anxiolytic and hypnotic effects. It is particularly beneficial in managing anxiety and insomnia, providing relief and promoting relaxation.
Used in Forensic Applications:
In the forensic field, ketazolam is utilized for its controlled substance status, aiding in the investigation and analysis of drug-related cases. Its psychotropic properties make it a relevant compound for understanding the effects of benzodiazepines on individuals and their potential involvement in criminal activities.
Originator
Anxon,Beecham,UK,1980
Manufacturing Process
A solution of 0.7 g of 2-(2-amino-N-methylacetamido)-5-chlorobenzophenone
in 10 ml of a 50% solution (by weight) of diketene in acetone is refluxed for 3
hours and then evaporated to give a brown oil. The oil is chromatographed on
200 g of silica gel using a 1:1 (by volume) mixture of ethyl acetate
cyclohexane; 25 ml fractions are collected. Fractions 11-14 are combined,
mixed with chloroform, evaporated and triturated with ether to give 0.337 g
of 11-chloro-8,12b-dihydro-2,8-dimethyl-12b-phenyl-4H-[1,3]oxazino[3,2-d]
[1.4] benzodiazepine-4,7(6H)-dione as a pale yellow solid, MP 174°C to
176°C.
Therapeutic Function
Antianxiety
Check Digit Verification of cas no
The CAS Registry Mumber 27223-35-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,2,2 and 3 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 27223-35:
(7*2)+(6*7)+(5*2)+(4*2)+(3*3)+(2*3)+(1*5)=94
94 % 10 = 4
So 27223-35-4 is a valid CAS Registry Number.
InChI:InChI=1/C20H17ClN2O3/c1-13-10-18(24)23-12-19(25)22(2)17-9-8-15(21)11-16(17)20(23,26-13)14-6-4-3-5-7-14/h3-11H,12H2,1-2H3
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