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27230-58-6

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27230-58-6 Usage

General Description

(5-bromofuran-2-yl)methanol is a chemical compound with the molecular formula C5H5BrO2. It is a furan derivative containing a bromine atom and a hydroxyl group. (5-bromofuran-2-yl)methanol is commonly used in the synthesis of pharmaceutical compounds and organic molecules due to its reactivity and versatility. It can also be used as a building block for the production of agrochemicals and pesticides. Additionally, (5-bromofuran-2-yl)methanol has been studied for its potential pharmacological properties, including its ability to act as an anticancer agent and an anti-inflammatory drug. Its unique structure and properties make it a valuable and important compound in the field of organic chemistry and pharmaceutical research.

Check Digit Verification of cas no

The CAS Registry Mumber 27230-58-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,2,3 and 0 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 27230-58:
(7*2)+(6*7)+(5*2)+(4*3)+(3*0)+(2*5)+(1*8)=96
96 % 10 = 6
So 27230-58-6 is a valid CAS Registry Number.

27230-58-6Relevant articles and documents

Intramolecular reactions of alkynes with furans and electron rich arenes catalyzed by PtCl2: The role of platinum carbenes as intermediates

Martin-Matute, Belen,Nevado, Cristina,Cardenas, Diego J.,Echavarren, Antonio M.

, p. 5757 - 5766 (2007/10/03)

5-(2-Furyl)-1-alkynes react, with PtCl2 as catalyst, to give phenols. On the basis of DFT calculations, a cyclopropyl platinacarbene complex was found as the key intermediate in the process. The cyclopropane and dihydrofuran rings of this intermediate open to form a carbonyl compound, which reacts with the platinum carbene to form an oxepin, which is in equilibrium with an arene oxide. When the reaction is carried out in the presence of water, dicarbonyl compounds are obtained, which support the proposed mechanism. Other cyclizations of alkynes with furans or electron-rich arenes give products of apparent Friedel-Crafts-type reactions, although these processes could also proceed by pathways involving the formation of cyclopropyl platinum carbenes.

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