27257-18-7 Usage
Chemical classification
2-(1-Methylethyl)-1H-pyrrolo[2,3-b]pyridine is a pyrrolopyridine derivative, which is a type of heterocyclic compound.
Molecular weight
The molecular weight of 2-(1-Methylethyl)-1H-pyrrolo[2,3-b]pyridine is 172.23 g/mol.
Structure
This compound has a bicyclic structure, with a pyrrole ring fused to a pyridine ring. The pyrrole ring is a five-membered ring with one nitrogen atom, while the pyridine ring is a six-membered ring with one nitrogen atom.
Substituent
2-(1-Methylethyl)-1H-pyrrolo[2,3-b]pyridine contains an isopropyl group attached to the pyrrole ring. The isopropyl group consists of a methyl group (CH3) attached to an ethyl group (C2H5).
Application in medicinal chemistry
This compound is used as a building block for the synthesis of various pharmaceutical compounds, making it an important substance in the field of medicinal chemistry.
Biological activities
2-(1-Methylethyl)-1H-pyrrolo[2,3-b]pyridine has been studied for its potential biological activities, including anticancer, antiviral, and antifungal properties. These properties make it a promising candidate for the development of new therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 27257-18-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,2,5 and 7 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 27257-18:
(7*2)+(6*7)+(5*2)+(4*5)+(3*7)+(2*1)+(1*8)=117
117 % 10 = 7
So 27257-18-7 is a valid CAS Registry Number.
InChI:InChI=1/C10H12N2/c1-7(2)9-6-8-4-3-5-11-10(8)12-9/h3-7H,1-2H3,(H,11,12)
27257-18-7Relevant articles and documents
NOVEL COMPOUNDS
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, (2009/01/20)
The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds according to formula (I) and salts thereof. The compounds of the invention are inhibitors of kinase activity, in particular IKK2 activity.
Reactions of β-(lithiomethyl)azines with nitriles as a route to pyrrolo-pyridines, - quinolines, -pyrazines, - quinoxalines and -pyrimidines
Davis, Michael L.,Wakefield, Basil J.,Wardell, Jacklyn A.
, p. 939 - 952 (2007/10/02)
Deprotonation of 3-methylazines, followed by reaction with benzonitile, gives an intermediate which, on treatment with additional strong base, cyclises to give 2-phenyl[1H]-pyrrolo[2,3-b]pyridine. The application of this type of reaction to a variety of n
