27258-80-6Relevant academic research and scientific papers
1,3-Dialkynyl- and 1,3-dialkenylisobenzofurans: New π-extended congeners prepared by double nucleophilic addition of alkynyllithiums to o-phthalaldehyde
Kudo, Ryoji,Kitamura, Kei,Hamura, Toshiyuki
, p. 25 - 28 (2017)
Efficient synthetic route to 1,3-dialkynyl- and 1,3-dialkenylisobenzofurans, new π-extended congeners of isobenzofurans, was reported. A three-step protocol including double nucleophilic additions of alkynyllithiums to o-phthalaldehyde and selective oxida
Recursive Anion-Triggered Tandem Reactions of ortho-Bis-ynones: Tunable Synthesis of 1-Indenones and Cyclopenta[ a]inden-8(2 H)-ones
Gunnam, Anilkumar,Balasubramani, Alagesan,Mehta, Goverdhan
, p. 4376 - 4384 (2022/03/15)
Recursive anion-mediated activation of o-bis-ynones sets off a Michael addition-aldol reaction-dehydrative rearrangement cascade, leading to the one-pot synthesis of 1-indenones via orthogonal interplay between the two ortho-ynone moieties. Repeating the recursive anion engagement with the 1-indenones unfolded access to a functionally embellished cyclopenta[a]inden-8(2H)-one core and its spiroannulated analogues either directly or stepwise through tandem 1,6-Michael-type addition-6πelectrocyclization and an in situ oxidation sequence.
Catalytic [2 + 2 + 2] and thermal [4 + 2] cycloaddition of 1,2-bis(arylpropiolyl)benzenes
Tanaka, Ken,Suda, Takeshi,Noguchi, Keiichi,Hirano, Masao
, p. 2243 - 2246 (2007/10/03)
We have determined that a cationic rhodium(I)/Segphos complex catalyzes an enantio- and diastereoselective intermolecular [2 + 2 + 2] cycloaddition of 1,2-bis(arylpropiolyl)benzenes with various monoalkynes at room temperature to give axially chiral 1,4-t
