27270-59-3Relevant academic research and scientific papers
Synthesis of highly functionalized chiral nitriles by radical fragmentation of β-hydroxy azides. Convenient transformation of aldononitriles into 1,4- and 1,5-iminoalditols
Hernandez, Rosendo,Leon, Elisa I.,Moreno, Pilar,Riesco-Fagundo, Concepcion,Suarez, Ernesto
, p. 8437 - 8444 (2007/10/03)
The synthesis of highly functionalized nitriles by an alkoxyl radical fragmentation of cyclic β-hydroxy azides is described. The alkoxyl radicals were generated by reaction of the alcohols with (diacetoxyiodo)benzene and iodine under mild conditions compa
Tin(II) Chloride Dihydrate - a Mild Reagent for the Transformation of 6-Nitro-Δ5-steroids to 5α-Hydroxy-6-ketosteroids
Singhal, Gireesh M.,Das, Nalin B.,Sharma, Ram P.
, p. 498 - 499 (2007/10/02)
Reaction of excess hydrated tin(II) chloride with 6-nitro-Δ5-steroids (1a-g) and (5) in tetrahydrofuran furnishes 5α-hydroxy-6-ketosteroids (2a-g) and (6) respectively, in good yields.
Synthesis of 3β-Hydroxy-6-cyano-B-norcholest-5-ene
Pai, K. G.,Sunthankar, S. V.
, p. 510 - 511 (2007/10/02)
3β-Acetoxy-5,6-secocholest-5-one-6-nitrile (I, R= -C8H17) prepared from cholesterol is cyclised to 3β-hydroxy-6-cyano-B-norcholest-5-ene (II) with sodium methoxide in methanol
