272776-12-2

Basic information

• Product Name: [1,1'-Binaphthalene]-2,2'-diol, (1S)-, coMpd. with 5-Methoxy-2-[(S)-[(4-Methoxy-3,5-diMethyl-2-pyridinyl)Methyl]sulfinyl]-1H-benziMidazole (1:1)
• Synonyms: [1,1'-Binaphthalene]-2,2'-diol, (1S)-, coMpd. with 5-Methoxy-2-[(S)-[(4-Methoxy-3,5-diMethyl-2-pyridinyl)Methyl]sulfinyl]-1H-benziMidazole (1:1)
• CAS NO: 272776-12-2
• Molecular Formula: C20H14O2.C17H19N3O3S
• EINECS: -0
• Mol File: 272776-12-2.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: [1,1'-Binaphthalene]-2,2'-diol, (1S)-, coMpd. with 5-Methoxy-2-[(S)-[(4-Methoxy-3,5-diMethyl-2-pyridinyl)Methyl]sulfinyl]-1H-benziMidazole (1:1)(CAS DataBase Reference)
• NIST Chemistry Reference: [1,1'-Binaphthalene]-2,2'-diol, (1S)-, coMpd. with 5-Methoxy-2-[(S)-[(4-Methoxy-3,5-diMethyl-2-pyridinyl)Methyl]sulfinyl]-1H-benziMidazole (1:1)(272776-12-2)
• EPA Substance Registry System: [1,1'-Binaphthalene]-2,2'-diol, (1S)-, coMpd. with 5-Methoxy-2-[(S)-[(4-Methoxy-3,5-diMethyl-2-pyridinyl)Methyl]sulfinyl]-1H-benziMidazole (1:1)(272776-12-2)

Safety Data

• Hazardous Substances Data: 272776-12-2(Hazardous Substances Data)

Upstream product

• 18531-99-2 (S)-[1,1']-binaphthalenyl-2,2'-diol 
• 73590-58-6 omeprazole 
• 73590-58-6 omeprazole 
• 161973-11-1 esomeprazole magnesium 

Relevant articles and documents

EFFICIENT PROCESS FOR THE PREPARATION OF ESOMEPRAZOLE (S)-BINOL COMPLEX

Object of the present invention is an improved process for the preparation of Esomeprazole (S)-BINOL complex which is a key intermediate for the synthesis of Esomeprazole and salts thereof.

PROCESS FOR THE RESOLUTION OF OMEPRAZOLE

The present invention relates to process for the resolution of omeprazole. The present invention further provides a novel compound of enantiomers of omeprazole cyclic amine salt and a process for preparing it. The present invention also provides a solid of (R)- or (S)-omeprazole cyclic amine salt and a process for preparing it. The present invention also provides a process for the preparation of esomeprazole magnesium dihydrate substantially free of its trihydrate form. The present invention also provides a process for the preparation of recovery of chiral BINOL.

PROCESS FOR THE PREPARATION OF ESOMEPRAZOLE

The invention relates to an improved process for preparation of esomeprazole or salts thereof by optical resolution of omeprazole with BINOL (1,1'-bi-2-naphthol).

S-OMEPRAZOLE STRONTIUM OR HYDRATE THEREOF, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME

This invention provides S-omeprazole strontium or a hydrate thereof for the prevention or treatment of a gastric acid-related disease, which has high optical purity, theremostability, solubility and nonhygroscopicity, a method for preparing same, and a pharmaceutical composition comprising same.