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5-methoxy-3-phenyl-1H-indole-2-carboxylic acid ethyl ester is a complex organic compound with the molecular formula C18H17NO3. It is a derivative of indole, a heterocyclic aromatic organic compound, and features a methoxy group at the 5-position, a phenyl group at the 3-position, and a carboxylic acid group at the 2-position. The ethyl ester functional group is attached to the carboxylic acid, making it a less acidic and more stable form of the parent compound. This chemical is primarily used in the synthesis of various pharmaceuticals and biologically active molecules due to its unique structure and properties. It is an important intermediate in the development of drugs targeting the serotonin receptor, which plays a crucial role in mood regulation and other physiological processes.

27294-08-2

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27294-08-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 27294-08-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,2,9 and 4 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 27294-08:
(7*2)+(6*7)+(5*2)+(4*9)+(3*4)+(2*0)+(1*8)=122
122 % 10 = 2
So 27294-08-2 is a valid CAS Registry Number.

27294-08-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name ethyl 5-methoxy-3-phenyl-1H-indole-2-carboxylate

1.2 Other means of identification

Product number -
Other names 5-methoxy-3-phenyl-indole-2-carboxylic acid ethyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:27294-08-2 SDS

27294-08-2Upstream product

27294-08-2Relevant academic research and scientific papers

Novel method for synthesis of aryl hydrazones from α-diazo esters: scope and limitations of nucleophiles

Yasui, Eiko,Wada, Masao,Takamura, Norio

experimental part, p. 461 - 468 (2009/04/06)

Aryl hydrazones, the precursor of Fischer indole synthesis, were easily obtained by nucleophilic addition of aryllithium reagents to diazo esters. The aryl hydrazones were converted into indoles in good yields by heating with thionyl chloride in alcohol.

Novel approach to arylhydrazones, the precursor for Fischer indole synthesis, via diazo esters derived from α-amino acid esters

Yasui, Eiko,Wada, Masao,Takamura, Norio

, p. 743 - 746 (2007/10/03)

A novel method for synthesizing arylhydrazones, the precursor for Fischer indole synthesis, using aryllithium reagents and α-diazo esters that are easily obtained from α-amino acid esters, is described.

3-substituted indole antiproliferative angiogenesis inhibitors

-

, (2008/06/13)

3-Substituted indole carbohydrazides having the formula are useful for inhibiting angiogenesis and cell proliferation. Also disclosed are compositions which inhibit angiogenesis and cell proliferation and methods of inhibiting angiogenesis and cancer in a mammal.

3-substituted indole angiogenesis inhibitors

-

, (2008/06/13)

3-Substituted indole carbohydrazides having the formula are useful for inhibiting angiogenesis. Also disclosed are angiogenesis-inhibiting compositions and methods of inhibiting angiogenesis in a mammal.

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