27295-64-3 Usage
General Description
4-Methyl-2,3-dihydro-1H-pyrrolo[3,4-c]quinoline-1,3-dione is a chemical compound with a molecular formula C15H10N2O2. It is a heterocyclic compound that contains a pyrroloquinoline core and a dione moiety. 4-METHYL-2,3-DIHYDRO-1H-PYRROLO[3,4-C]QUINOLINE-1,3-DIONE has potential pharmacological activities and is being studied for its potential therapeutic applications in various diseases. It may also have applications in the field of organic synthesis and medicinal chemistry. The exact properties and uses of this compound are still under investigation, and further research is needed to fully understand its potential applications.
Check Digit Verification of cas no
The CAS Registry Mumber 27295-64-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,2,9 and 5 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 27295-64:
(7*2)+(6*7)+(5*2)+(4*9)+(3*5)+(2*6)+(1*4)=133
133 % 10 = 3
So 27295-64-3 is a valid CAS Registry Number.
InChI:InChI=1/C12H8N2O2/c1-6-9-10(12(16)14-11(9)15)7-4-2-3-5-8(7)13-6/h2-5H,1H3,(H,14,15,16)
27295-64-3Relevant articles and documents
1,3-Dioxo-4-methyl-2,3-dihydro-1H-pyrrolo[3,4-c]quinolines as potent caspase-3 inhibitors
Kravchenko, Dmitri V.,Kysil, Vladimir V.,Ilyn, Alexey P.,Tkachenko, Sergey E.,Maliarchouk, Sergey,Okun, Ilya M.,Ivachtchenko, Alexandre V.
, p. 1841 - 1845 (2007/10/03)
Synthesis, biological evaluation and structure-activity relationships for a series of novel nonpeptide small molecule inhibitors of caspase-3 are described. Among the studied compounds, 8-sulfamide derivatives of 1,3-dioxo-4-methyl-2,3-dihydro-1H-pyrrolo[3,4-c]quinolines have been identified as potent inhibitors of caspases-3. The most active compound within this series (8f) inhibited caspase-3 with IC50 = 4 nM.
