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273207-57-1

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273207-57-1 Usage

General Description

3-Methylene-8-Boc-8-Azabicyclo[3.2.1]Octane is a chemical compound with a complex structure containing a bicyclic skeleton and various functional groups. The name "3-Methylene" indicates the presence of a methylene group at the third carbon atom of the molecule, while "8-Boc" refers to a tert-butoxycarbonyl group attached to the eighth carbon atom. The "8-Azabicyclo[3.2.1]Octane" portion of the name signifies the presence of a nitrogen atom in the bicyclic ring system. 3-Methylene-8-Boc-8-Azabicyclo[3.2.1]Octane has potential applications in organic synthesis and medicinal chemistry, particularly in the development of pharmaceuticals and bioactive molecules due to its unique structure and functional groups. Further research and analysis are necessary to fully understand the properties and potential uses of this chemical.

Check Digit Verification of cas no

The CAS Registry Mumber 273207-57-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,7,3,2,0 and 7 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 273207-57:
(8*2)+(7*7)+(6*3)+(5*2)+(4*0)+(3*7)+(2*5)+(1*7)=131
131 % 10 = 1
So 273207-57-1 is a valid CAS Registry Number.

273207-57-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name tert-butyl 3-methylidene-8-azabicyclo[3.2.1]octane-8-carboxylate

1.2 Other means of identification

Product number -
Other names 3-methylene-8-aza-bicyclo[3.2.1]octane-8-carboxylic acid tert-butyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:273207-57-1 SDS

273207-57-1Relevant articles and documents

INHIBITORS OF HISTONE DEACETYLASE USEFUL FOR THE TREATMENT OR PREVENTION OF HIV INFECTION

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Page/Page column 58, (2020/06/01)

The present invention relates to Compounds of Formula I: and pharmaceutically acceptable salts or prodrug thereof, wherein R1, R2, R3, R4 and A are as defined herein. The present invention also relates to compos

Dehydroxymethylation of Alcohols Enabled by Cerium Photocatalysis

Zhang, Kaining,Chang, Liang,An, Qing,Wang, Xin,Zuo, Zhiwei

supporting information, p. 10556 - 10564 (2019/08/28)

Dehydroxymethylation, the direct conversion of alcohol feedstocks as alkyl synthons containing one less carbon atom, is an unconventional and underexplored strategy to exploit the ubiquity and robustness of alcohol materials. Under mild and redox-neutral reaction conditions, utilizing inexpensive cerium catalyst, the photocatalytic dehydroxymethylation platform has been furnished. Enabled by ligand-to-metal charge transfer catalysis, an alcohol functionality has been reliably transferred into nucleophilic radicals with the loss of one molecule of formaldehyde. Intriguingly, we found that the dehydroxymethylation process can be significantly promoted by the cerium catalyst, and the stabilization effect of the fragmented radicals also plays a significant role. This operationally simple protocol has enabled the direct utilization of primary alcohols as unconventional alkyl nucleophiles for radical-mediated 1,4-conjugate additions with Michael acceptors. A broad range of alcohols, from simple ethanol to complex nucleosides and steroids, have been successfully applied to this fragment coupling transformation. Furthermore, the modularity of this catalytic system has been demonstrated in diversified radical-mediated transformations including hydrogenation, amination, alkenylation, and oxidation.

NOVEL KINASE INHIBITORS

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Paragraph 0211, (2014/05/07)

The present invention provides derivatives of thiazolylamino-substituted heterocycles. These compounds are inhibitors of kinases, including compounds that show antiproliferative activity against cells, including against tumor cells, and are useful in the treatment of diseases including cancer.

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