β-Tetraacetyl-streptozotocin (β-TAS) is a chemical derivative of the naturally occurring antibiotic streptozotocin, which is produced by Streptomyces achromogenes. β-Tetraacetyl-streptozotocin is characterized by the presence of four acetyl groups attached to the glucosamine moiety of streptozotocin, which protect the molecule from hydrolysis and degradation. β-TAS is often used as a prodrug in medical research and clinical applications, as it can be administered in a more stable form and then metabolized in the body to release the active streptozotocin. This active form is known to have cytotoxic effects, particularly against certain types of cancer cells, and is used in chemotherapy regimens. The acetylation of streptozotocin in β-TAS allows for better control over its release and activity, making it a valuable tool in the development of targeted cancer therapies.
The CAS Registry Mumber 27321-18-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,3,2 and 1 respectively; the second part has 2 digits, 1 and 8 respectively. Calculate Digit Verification of CAS Registry Number 27321-18: (7*2)+(6*7)+(5*3)+(4*2)+(3*1)+(2*1)+(1*8)=92 92 % 10 = 2 So 27321-18-2 is a valid CAS Registry Number.
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