273401-69-7Relevant academic research and scientific papers
TRICYCLIC COMPOUNDS
-
Paragraph 1738-1739, (2014/06/25)
The present invention provides a compound of formula I or a pharmaceutically acceptable salt thereof; and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
Selective inhibitors of EG5 motors and methods of use
-
Page/Page column 36-37, (2013/03/26)
Embodiments of the present invention comprises a compound of formula I or its enantiomer, diastereomer, stereoisomer or its pharmaceutically acceptable salt, methods of use and methods of synthesis.
Synthesis and characterization of tritylthioethanamine derivatives with potent KSP inhibitory activity
Rodriguez, Delany,Ramesh, Chinnasamy,Henson, Lauren H.,Wilmeth, Lori,Bryant, Bj K.,Kadavakollu, Samuel,Hirsch, Rebecca,Montoya, Johnelle,Howell, Porsha R.,George, Jon M.,Alexander, David,Johnson, Dennis L.,Arterburn, Jeffrey B.,Shuster, Charles B.
experimental part, p. 5446 - 5453 (2011/10/19)
Assembly of a bipolar mitotic spindle requires the action of class 5 kinesins, and inhibition or depletion of this motor results in mitotic arrest and apoptosis. S-Trityl-l-cysteine is an allosteric inhibitor of vertebrate Kinesin Spindle Protein (KSP) th
Aminosulf(ox)ides as Ligands for Iridium(I)-Catalyzed Asymmetric Transfer Hydrogenation
Petra, Danielle G. I.,Kamer, Paul C. J.,Spek, Anthony L.,Schoemaker, Hans E.,Van Leeuwen, Piet W. N. M.
, p. 3010 - 3017 (2007/10/03)
A new class of efficient catalysts was developed for the asymmetric transfer hydrogenation of unsymmetrical ketones. A series of chiral N,S-chelates (6-22) was synthesized to serve as ligands in the iridium(I)-catalyzed reduction of ketones. Both formic a
