273733-97-4

Upstream product

• 273733-90-7 (2R,4S)-1-benzyloxy-2-methyl-6-hepten-4-yl-propenoate 
• 273733-92-9 (2S,6R)-6-allyl-2-[(2R)-3-benzyloxy-2-methyl-propyl]-3,6-dihydro-2H-pyran 
• 1027233-25-5 Acetic acid (S)-6-((R)-3-benzyloxy-2-methyl-propyl)-5,6-dihydro-2H-pyran-2-yl ester 
• 273733-91-8 (S)-6-((R)-3-(benzyloxy)-2-methylpropyl)-5,6-dihydro-2H-pyran-2-one 
• 273733-89-4 (4S,6R)-7-(benzyloxy)-6-methylhept-1-en-4-ol 
• 104265-24-9 (3R)-4-benzyloxy-3-methyl-butanonitrile 
• 80910-01-6 (S)-2-[(4-methoxybenzyloxy)methyl]oxirane 
• 90865-70-6 [3R]-4-Benzyloxy-3-methylbutanal 
• 34097-60-4 methyl benzenesulfonylacetate 
• 273733-93-0 (2S,6R)-6-Allyl-2-((R)-3-iodo-2-methyl-propyl)-3,6-dihydro-2H-pyran 
• 273733-96-3 (5S)-5-(p-methoxy-benzyl)-methyl-3-phenyl-sulphonyl-dihydrofuran-2-one 

Downstream Products

• 273733-98-5 (2S,4S)-2-[(R)-3-((2R,6R)-6-Allyl-3,6-dihydro-2H-pyran-2-yl)-2-methyl-propyl]-2-benzenesulfonyl-5-(4-methoxy-benzyloxy)-pentane-1,4-diol 

Relevant academic research and scientific papers

An enantioselective synthesis of the C2-C16 segment of antitumor macrolide laulimalide

An enantioselective synthesis of the C2-C16 segment of the novel antitumor agent laulimalide is described. The key steps involve a highly diastereoselective allylation, ring-closing olefin metathesis of a homoallylic alcohol derived acrylate ester, a stereoselective anomeric alkylation and an elaboration of an exo-methylene unit by a Julia olefination reaction. (C) 2000 Elsevier Science Ltd.