273738-41-3

Upstream product

• 176900-63-3 (2S,4R)-5-{[tert-butyl(diphenyl)silyl]oxy}-2,4-dimethylpentyl acetate 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 90270-02-3 (2R,4S)-1-hydroxy-2,4-dimethylpentyl acetate 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 43043-17-0 (2S,3S,4R,6R)-3-hydroxy-2,4,6-trimethyl-octanoic acid (1S,2R,4R)-1-((S)-1-carboxyethyl)-2,4-dimethyl-hexyl ester 
• 1373758-76-9 tert-butyl[(2R,4R)-2,4-dimethylhexyloxy]diphenylsilane 
• 273738-43-5 Toluene-4-sulfonic acid (E)-(2R,6S,8R)-9-(tert-butyl-diphenyl-silanyloxy)-2,4,6,8-tetramethyl-non-3-enyl ester 
• 273738-38-8 Toluene-4-sulfonic acid (E)-(2S,6S,8R)-9-(tert-butyl-diphenyl-silanyloxy)-2,4,6,8-tetramethyl-non-3-enyl ester 
• 273738-37-7 (E)-(2S,6S,8R)-9-(tert-Butyl-diphenyl-silanyloxy)-2,4,6,8-tetramethyl-non-3-enoic acid methyl ester 
• 273738-52-6 (E)-(2S,6S,8R)-9-(tert-butyldiphenylsiloxy)-2,4,6,8-tetramethyl-3-nonen-1-ol 
• 273738-36-6 tert-Butyl-((2R,4S)-2,4-dimethyl-hept-6-ynyloxy)-diphenyl-silane 

Relevant academic research and scientific papers

Chemoenzymatic approach to the total synthesis of (+)-bourgeanic acid

A highly stereoselective total synthesis of (+)-bourgeanic acid has been accomplished by an enzymatic desymmetrization approach to create two methyl chiral centers. Other key steps involved in this approach are a Wittig reaction, a Gilman reaction, and TE

Synthesis (and alternative proof of configuration) of the scyphostatin C(1')-C(20') trienoyl fragment.

[reaction--see text] Each of four diastereomers of structure 2, corresponding to the lipophilic side chain of scyphostatin (1), were prepared. Careful analysis of their NMR spectral data and comparison with those of the natural product corroborates the re