273749-25-0

Basic information

• Product Name: (2,3-DIAMINOPHENYL)METHANOL
• Synonyms: (2,3-DIAMINOPHENYL)METHANOL;Benzenemethanol,2,3-diamino-
• CAS NO: 273749-25-0
• Molecular Formula: C₇H₁₀N₂O
• Molecular Weight: 138.17
• Product Categories: pharmacetical
• Mol File: 273749-25-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 353.2°Cat760mmHg
• Flash Point: 167.4°C
• Appearance: /
• Density: 1.281g/cm³
• Vapor Pressure: 1.34E-05mmHg at 25°C
• Refractive Index: 1.689
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• CAS DataBase Reference: (2,3-DIAMINOPHENYL)METHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: (2,3-DIAMINOPHENYL)METHANOL(273749-25-0)
• EPA Substance Registry System: (2,3-DIAMINOPHENYL)METHANOL(273749-25-0)

Safety Data

• Hazardous Substances Data: 273749-25-0(Hazardous Substances Data)

Usage

General Description

(2,3-Diaminophenyl)methanol is a chemical compound with the molecular formula C7H10N2O. It is a white to beige crystalline powder that is sparingly soluble in water and organic solvents. (2,3-DIAMINOPHENYL)METHANOL is used in the production of various substances such as p-aminosalicylic acid, which is used in the treatment of tuberculosis. It can also be used as a building block in the synthesis of pharmaceuticals and organic compounds. Additionally, (2,3-diaminophenyl)methanol has potential applications in the field of materials science, particularly in the development of polymers and electronic materials. However, it is important to handle this chemical with care, as it may pose health risks if not properly managed and used.

InChI:InChI=1/C7H10N2O/c8-6-3-1-2-5(4-10)7(6)9/h1-3,10H,4,8-9H2

Upstream product

• 16406-00-1 4-hydroxymethyl-2,1,3-benzothiadiazole 
• 16405-99-5 4-(bromomethyl)benzo[c][1,2,5]thiadiazole 
• 1457-92-7 4-Methyl-2,1,3-benzothiadiazol 
• 151869-78-2 4-dibromomethyl-2,1,3-benzothiadiazole 
• 5170-68-3 benzo[c][1,2,5]thiadiazole-4-carbaldehyde 

Downstream Products

• 273749-26-1 4-hydroxymethyl-2-(2-nitrophenyl)-benzimidazole 
• 948834-71-7 C₁₆H₁₆O₂N₅Br 
• 948834-70-6 C₂₀H₂₆N₅O₂BrSi 
• 948834-63-7 C₁₅H₁₄O₂N₅Br 
• 867339-08-0 {4-[2-(4-hydroxymethyl-1H-benzoimidazol-2-yl)-phenylsulfamoyl]-phenoxy}-acetic acid ethyl ester 
• 916326-41-5 3-(tert-butyl-dimethyl-silanyloxymethyl)-benzene-1,2-diamine 
• 916325-86-5 3-(methoxymethyl)benzene-1,2-diamine 

Relevant articles and documents

Biomimetic hydrogen-bonding cascade for chemical activation: telling a nucleophile from a base

Hydrogen bonding-assisted polarization is an effective strategy to promote bond-making and bond-breaking chemical reactions. Taking inspiration from the catalytic triad of serine protease active sites, we have devised a conformationally well-defined benzimidazole platform that can be systematically functionalized to install multiple hydrogen bonding donor (HBD) and acceptor (HBA) pairs in a serial fashion. We found that an increasing number of interdependent and mutually reinforcing HBD-HBA contacts facilitate the bond-forming reaction of a fluorescence-quenching aldehyde group with the cyanide ion, while suppressing the undesired Br?nsted acid-base reaction. The most advanced system, evolved through iterative rule-finding studies, reacts rapidly and selectively with CN- to produce a large (>180-fold) enhancement in the fluorescence intensity at λmax = 450 nm.

BENZIMIDAZOLE DERIVATIVES USEFUL AS POTASSIUM CHANNEL INHIBITORS

The present invention relates to compounds of the general formula (I). The compounds of formula I are potassium channel inhibitors useful for treatment of a cardiac disease, disorder or condition in a mammal.