273753-65-4Relevant academic research and scientific papers
A stereoselective synthesis of the C13-C19 fragment of sanglifehrin A
Hall, Philip,Brun, Jvan,Denni, Donatienne,Metternich, Rainer
, p. 315 - 318 (2007/10/03)
A short, stereoselective route to the C13-C19 fragment of the immunosuppressant sanglifehrin A 1, is presented. The key step involves a highly diastereoselective boron aldol reaction between β-ketoimide 11 and triisopropylsilyl propargyl aldehyde 21c.
