27376-76-7 Usage
Description
13,14-Dihydro-15-keto prostaglandin F2alpha (PGF2α) is a prostaglandin Falpha derived from prostaglandin F2alpha through formal oxidation of the 15-hydroxy group and hydrogenation of the 13,14-double bond. It is a bioactive lipid mediator that plays a role in various physiological processes, including inflammation, blood clotting, and vascular function.
Uses
Used in Pharmaceutical Industry:
13,14-Dihydro-15-keto PGF2α is used as a therapeutic agent for its potential anti-inflammatory and vasodilatory properties. It may be employed in the treatment of various conditions, such as asthma, allergies, and cardiovascular diseases, where modulation of prostaglandin levels can be beneficial.
Used in Research Applications:
In the field of scientific research, 13,14-Dihydro-15-keto PGF2α is used as a research tool to study the role of prostaglandins in various biological processes. It can be utilized to investigate the mechanisms of inflammation, blood clotting, and vascular function, as well as to develop new drugs targeting these pathways.
Used in Veterinary Medicine:
13,14-Dihydro-15-keto PGF2α is used as a veterinary drug, particularly in the treatment of reproductive issues in animals. It may be employed to induce labor, regulate the estrous cycle, or treat certain fertility problems in livestock.
Used in Biochemical Assays:
In the field of biochemistry, 13,14-Dihydro-15-keto PGF2α is used as a substrate or inhibitor in various assays to study the activity of enzymes, such as acetylcholine esterase, which it binds to. This can help researchers understand the interactions between prostaglandins and other biomolecules, as well as develop new drugs targeting these interactions.
Check Digit Verification of cas no
The CAS Registry Mumber 27376-76-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,3,7 and 6 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 27376-76:
(7*2)+(6*7)+(5*3)+(4*7)+(3*6)+(2*7)+(1*6)=137
137 % 10 = 7
So 27376-76-7 is a valid CAS Registry Number.
InChI:InChI=1/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,16-19,22-23H,2-3,5-6,8-14H2,1H3,(H,24,25)/b7-4-/t16-,17-,18+,19-/m1/s1
27376-76-7Relevant articles and documents
TOTAL SYNTHESIS OF 15-OXO-13,14-DIHYDRO-PROSTAGLANDIN F2α, A MAJOR METABOLITE OF PROSTAGLANDIN F2α
Marczak, S.,Wicha, J.
, p. 633 - 640 (2007/10/02)
The synthesis of prostaglandin F2α metabolite starting from Corey lactone is described.The key step of the synthesis involves chemoselective Wittig reaction.
