273926-25-3

Upstream product

• 273926-22-0 (E)-3-((2R,3R,4S,5R,6S)-4,5-Bis-benzyloxy-6-methoxy-2-prop-2-ynyl-tetrahydro-pyran-3-yloxy)-acrylic acid ethyl ester 
• 90633-95-7 methyl 2,3-bis-O-benzyl-4-O-[(4-methoxyphenyl)methyl]-α-D-glucopyranoside 
• 273926-19-5 (2R,3R,4S,5R,6S)-4,5-Bis-benzyloxy-6-methoxy-2-prop-2-ynyl-tetrahydro-pyran-3-ol 
• 273926-16-2 (2S,3R,4S,5R,6R)-3,4-Bis-benzyloxy-2-methoxy-5-(4-methoxy-benzyloxy)-6-prop-2-ynyl-tetrahydro-pyran 
• 273926-06-0 methyl-2,3-di-O-benzyl-6-iodo-4-O-(4-methoxybenzyl)-6-deoxy-α-D-glucopyranoside 

Downstream Products

• 273926-10-6 ((2R,3S,4aR,6S,7R,8S,8aR)-7,8-Bis-benzyloxy-3-hydroxy-6-methoxy-octahydro-pyrano[3,2-b]pyran-2-yl)-acetic acid ethyl ester 
• 273926-11-7 [(2R,3S,4aR,6S,7R,8S,8aR)-7,8-Bis-benzyloxy-3-(tert-butyl-dimethyl-silanyloxy)-6-methoxy-octahydro-pyrano[3,2-b]pyran-2-yl]-acetic acid ethyl ester 

Relevant academic research and scientific papers

Radical cyclization of sugar-derived β-(alkynyloxy)acrylates: Synthesis of novel fused ethers

(equation presented) Tributyltin radical mediated cyclization of carbohydrate-derived β-(alkynyloxy)acrylates leading to highly functionalized cis-and trans-fused bicyclic ethers of various ring sizes is described. The efficacy of the radical cyclization is nicely illustrated in the iterative construction of a frans-fused tricyclic tetrahydropyran.