273933-20-3Relevant academic research and scientific papers
Synthesis, cholinesterase inhibition and molecular modelling studies of coumarin linked thiourea derivatives
Saeed, Aamer,Zaib, Sumera,Ashraf, Saba,Iftikhar, Javeria,Muddassar, Muhammad,Zhang, Kam Y.J.,Iqbal, Jamshed
, p. 58 - 63 (2015)
Alzheimer's disease is among the most widespread neurodegenerative disorder. Cholinesterases (ChEs) play an indispensable role in the control of cholinergic transmission and thus the acetylcholine level in the brain is enhanced by inhibition of ChEs. Coum
Rapid synthesis of N-acyl ureas from their thio analogues using wet silica-supported permanganate under solvent-free conditions
Li, Zheng,Yu, Jin-Lan,Shi, Sheng-Yi,Zhu, Wei
, p. 1031 - 1037 (2007/10/03)
A rapid method to N-acyl ureas from corresponding N-acyl thioureas is described. N-coumaroyl-N′-arylthioureas, which are easily prepared by the reaction of coumarin-3-carboxylic acid chloride with potassium thiocyanate and arylamines, can be expeditiously
