274264-54-9

Upstream product

• 702711-14-6 (5R)-3-benzoyl-5-[(benzyloxy)methyl]-1,3-oxazolidin-2-one 
• 100-51-6 benzyl alcohol 
• 32315-10-9 bis(trichloromethyl) carbonate 
• 61248-83-7 (2R)-1-amino-3-(benzyloxy)propan-2-ol 
• 14618-80-5 (R)-benzyl glycidol 
• 702711-13-5 (1S)-2-(benzyloxy)-1-[(phenylseleno)methyl]ethylbenzoylcarbamate 

Downstream Products

• 61248-83-7 (2R)-1-amino-3-(benzyloxy)propan-2-ol 
• 97859-49-9 (R)-5-(hydroxymethyl)-1,3-oxazolidin-2-one 

Relevant academic research and scientific papers

METHOD FOR PREPARING OXAZOLIDINONE INTERMEDIATE

The invention relates to a method for preparing an oxazolidinone intermediate. Specifically, a synthesis procedure for the intermediate comprises: directly performing a “one-pot” reaction on a compound I, compound J or compound L without performing isolation, wherein a salt of a compound K is selected from a hydrochloride, sulfate, malate, tartrate, p-toluenesulfonate, or lactate, and wherein the symbol * in a compound indicates an atom of an R-type chirality or an S-type chirality or a racemate thereof.

Ring-Closure Reactions through Intramolecular Displacement of the Phenylselenonyl Group by Nitrogen Nucleophiles: A New Stereospecific Synthesis of N-Tosyl and N-Benzoyl-1,3-oxazolidin-2-ones from β-Hydroxyalkyl Phenyl Selenides

A new and convenient method for the stereospecific synthesis of variously substituted 1,3-oxazolidin-2-ones from the easily available β-hydroxyalkyl phenyl selenides is presented. After transformation into the N-tosyl or N-benzoyl carbamates, the selenide