27428-84-8

Usage

Uses

Used in Pharmaceutical Industry:
3-(Trichloromethyl)benzoyl chloride is used as an acylating agent for the synthesis of various pharmaceutical compounds. Its reactivity allows for the formation of benzoyl derivatives, which are important intermediates in the development of drugs with diverse therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, 3-(Trichloromethyl)benzoyl chloride serves as a key intermediate in the production of agrochemicals. Its ability to form benzoyl derivatives makes it valuable for the synthesis of active ingredients in pesticides and other agricultural chemicals.
Used in Dye Industry:
3-(Trichloromethyl)benzoyl chloride is utilized as a reagent in the manufacture of dyes. Its role in creating benzoyl derivatives contributes to the development of a wide range of dye products used in various applications, including textiles, plastics, and printing inks.
Used in Organic Synthesis:
3-(Trichloromethyl)benzoyl chloride is employed as a versatile reagent in organic synthesis. Its high reactivity and acylating properties make it suitable for the preparation of a variety of organic compounds, including those used in research, specialty chemicals, and other industrial applications.
Note: Due to the hazardous nature of 3-(Trichloromethyl)benzoyl chloride, it should be handled and stored with extreme care to prevent violent reactions with water, alcohols, and amines.

InChI:InChI=1/C8H4Cl4O/c9-7(13)5-2-1-3-6(4-5)8(10,11)12/h1-4H

Upstream product

• 881-99-2 1,3-bis-trichloromethyl-benzene 
• 1711-06-4 3-Methylbenzoyl chloride 
• 99-04-7 m-Toluic acid 

Downstream Products

• 27466-80-4 3-trichloromethyl-benzoic acid 
• 121-91-5 isophthalic acid 
• 709-61-5 3-Trichlormethyl-phenylisocyanat 
• 328-99-4 m-(trifluoromethyl)benzoyl fluoride 
• 726-32-9 N-<3-Trichlormethyl-phenyl>-carbaminsaeureisopropylester 
• 722-07-6 N-(3-trichloromethylphenyl)-N',N'-dimethylurea 
• 722-09-8 N-<3-Chlormethyl-phenyl>-urethan 

Relevant academic research and scientific papers

A O-between the - trifluoromethyl benzoic acid to synthetic method (by machine translation)

The present invention provides a O-between the - trifluoromethyl benzoic acid to the synthesis method, the method comprises the following steps: (1) between adjacent to methyl benzoic acid acylated preparation between neighbour methyl benzoyl chloride; (2) between the adjacent methyl benzoyl chloride to chlorine light between neighbour trichloromethyl benzoyl chloride is obtained; (3) adjacent to the trichloromethyl benzoyl chloride fluoride obtained between between neighbour trifluoromethyl methyl benzoyle fluoride; (4) adjacent to the trifluoromethyl benzoyle fluoride hydrolysis between the final product is obtained between neighbour trifluoromethyl methyl benzoic acid. The method of the invention cheap raw material, the product yield is high, the process is simple, is favorable for industrial production. (by machine translation)

Synthesis method of o-trifluoromethyl methyl benzoate, m-trifluoromethyl methyl benzoate and p-trifluoromethyl methyl benzoate

The invention provides a synthesis method of o-trifluoromethyl methyl benzoate, m-trifluoromethyl methyl benzoate and p-trifluoromethyl methyl benzoate. The synthesis method comprises the following steps: taking methyl benzoic acid as a raw material, carrying out acylating chlorination to obtain methylbenzoyl chloride, carrying out side-chain chlorination to obtain trichloromethyl benzoyl chloride, carrying out fluorination substitution to obtain trifluoromethyl benzoyl fluoride, and carrying out esterification to obtain a final product which is trifluoromethyl methyl benzoate. The synthesis method can be used for producing the o-trifluoromethyl methyl benzoate, the m-trifluoromethyl methyl benzoate and the p-trifluoromethyl methyl benzoate, is easily available in raw material, mild in reaction mechanism, high in reaction yield, few in reaction by-products, low in yield of three wastes and easy in treatment of three wastes, and is suitable for industrial production.