2743-80-8 Usage
Molecular Weight
339.36 g/mol The relative molecular mass of the compound based on the atomic weights of its constituent elements.
Structure
Isoindole-1,3(2H)-dione core The central structure of the compound is an isoindole-1,3(2H)-dione, which is a fused bicyclic ring system with two oxygen atoms in the dione form.
Side Chain 1
3,4-Dimethoxyphenyl One side chain attached to the isoindole core is a phenyl ring with two methoxy groups (-OCH3) attached at the 3rd and 4th positions.
Side Chain 2
Methyl-2-oxoethyl The other side chain is a 2-oxoethyl group (a 2-ketoethyl group) with a methyl group (-CH3) attached to it.
Chiral Center
R-enantiomeric form The compound has a chiral center, which gives it the R-enantiomeric form, meaning it has a specific three-dimensional arrangement of its atoms.
Optical Activity
Exhibits optical activity Due to the presence of the chiral center, the compound exhibits optical activity, which means it can rotate plane-polarized light.
Potential Applications
Pharmaceuticals or organic synthesis The unique structure of the compound suggests that it may have potential applications in pharmaceuticals or organic synthesis, although further research and testing are required to determine its properties and uses.
Check Digit Verification of cas no
The CAS Registry Mumber 2743-80-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,7,4 and 3 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 2743-80:
(6*2)+(5*7)+(4*4)+(3*3)+(2*8)+(1*0)=88
88 % 10 = 8
So 2743-80-8 is a valid CAS Registry Number.
2743-80-8Relevant academic research and scientific papers
Ferric Chloride-Catalyzed Acylation of Aromatic Compounds with N-Phthaloyl-α-amino Acyl Chlorides without Racemisation
Effenberger, Franz,Steegmueller, Dieter
, p. 117 - 124 (2007/10/02)
Reactive aromatic compounds are acylated without racemisation to aryl 1-phthalimidoalkyl ketones 4 in good yields with N-phthaloyl-α-amino acid chlorides in the presence of catalytic amounts (1 to 5 mol-percent) of FeCl3.This new method is especially useful for the synthesis of the pharmacologically interesting alkoxyaryl 1-phthalimidoalkyl ketones 6, 8, 10, and 11, which cannot be prepared in reasonable yields in the presence of other FC catalysts such as AlCl3 or SnCl4.
Intramolecular Friedel-Crafts Acylation of N-Phthaloyl-Substituted Arylalanyl and Homophenylalanyl Chlorides
Effenberger, Franz,Steegmueller, Dieter,Null, Volker,Ziegler, Thomas
, p. 125 - 130 (2007/10/02)
N-Phthaloyl-protected arylalanyl and homophenylalanyl chlorides 5 are acylated intramolecularly to 2-phthalimido-1-indanones 6 and -1-tetralone (6d) with AlCl3 (two-fold molar amounts) or catalytic amounts of FeCl3.The cycloacylation to the tetralone 6d with AlCl3 or FeCl3 proceeds without racemisation in very good yields, whereas the cycloacylation to the indanone 6a with FeCl3 gives rise to racemisation.Mixed anhydrides 11 of N-phthaloyl-α-amino acids and trifluoromethanesulfonate were prepared from the N-phthaloylamino acid chlorides and silver triflate.Acylation of arenes 12 with 11a as well as cycloaddition of (S)-O-methyl-N-phthaloyltyrosine triflate can be achieved without racemisation and without a catalyst.
