27443-47-6 Usage
Uses
Used in Pharmaceutical and Agrochemical Industries:
4-Diethoxymethyl-pyridine-2-carbonitrile serves as a key building block in the synthesis of various pharmaceuticals and agrochemicals, leveraging its versatile reactivity and functional groups to contribute to the development of new and effective compounds.
Used as a Pesticide:
4-Diethoxymethyl-pyridine-2-carbonitrile exhibits biological activity that makes it suitable for use as a pesticide, providing a means for controlling pests in agricultural settings.
Used in Disease Treatment Research:
4-Diethoxymethyl-pyridine-2-carbonitrile is under investigation for its potential use in the treatment of certain diseases, indicating its possible role in medical research and development for therapeutic applications.
Used in Laboratory and Industrial Settings:
Due to its low acute toxicity, 4-Diethoxymethyl-pyridine-2-carbonitrile is considered relatively safe for handling in both laboratory and industrial environments, contributing to its wide use in chemical synthesis and research processes.
Check Digit Verification of cas no
The CAS Registry Mumber 27443-47-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,4,4 and 3 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 27443-47:
(7*2)+(6*7)+(5*4)+(4*4)+(3*3)+(2*4)+(1*7)=116
116 % 10 = 6
So 27443-47-6 is a valid CAS Registry Number.
InChI:InChI=1/C11H14N2O2/c1-3-14-11(15-4-2)9-5-6-13-10(7-9)8-12/h5-7,11H,3-4H2,1-2H3
27443-47-6Relevant academic research and scientific papers
S-adenosylmethionine decarboxylase inhibitors: New aryl and heteroaryl analogues of methylglyoxal bis(guanylhydrazone)
Stanek,Caravatti,Capraro,Furet,Mett,Schneider,Regenass
, p. 46 - 54 (2007/10/02)
A series of 3-acylbenzamidine (amidino)hydrazones 7a-h, the corresponding (hetero)aromatic congeners 7i-p, and 3,3'-bis-amidino-biaryls 25a-e were synthesized. The hydrazones 7a-p were prepared by conversion of the corresponding acyl nitriles 1a,c-d,i,n-p to the imido esters 3a,c-d,i and the amidines 5a,c-d,h-i, followed by a reaction with aminoguanidine, or vice versa. Similarly, the biaryl 3,3'-dinitriles 23a-e were converted, via the imino esters 24a-c or the imino thioesters 27d-e, to the diamidines 25a-e. These new products are conformationally constrained analogues of methylglyoxal bis(guanylhydrazone) (MGBG). They are up to 100 times more potent as inhibitors of rat liver S-adenosylmethionine decarboxylase (SAMDC) and generally less potent inhibitors of rat small intestine diamine oxidase (DAO) than MGBG. Some of these SAMDC inhibitors, e.g., compounds 7a, 7e, 7i, 25a, and 25d, have shown antiproliferative effects against T24 human bladder carcinoma cells. These products, whose structure-activity relationships are discussed, are of interest as potential anticancer agents and drugs for the treatment of protozoal and Pneumocystis carinii infections.
