27468-37-7Relevant academic research and scientific papers
PHOSPHINE COMPOUND, INTERMEDIATE, PALLADIUM-COMPLEX, AND USE THEREOF
-
Page/Page column 43, (2010/02/08)
Palladum-phosphine complexes obtained by reacting a 5 compound of formula (1) below with a palladium compound: F(I) (wherein Ris a hydrogen atom, an alkyl group, a cycloalkyl group or a phenyl group which may be substituted; R and R are each, the same or different, an alkyl group, a cycloalkyl group or a phenyl group which may be substituted; R and R are each, the same or different, a hydrogen atom, an alkyl group, a cycloalkyl group or a phenyl group which may be substituted; R, R, R and R are each, the same or different, an alkyl group, a cycloalkyl group, a phenyl group which may be substituted, an alkoxyl group, a dialkylamino group, a halogen atom, a phenyl group, a benzyl group, a naphthyl group or a halogenated alkyl group; R and R, R and R may be combined to form, each, a fused ring, a trimethylene group, a tetramethylene group or a 20 methylenedioxy group; p, q, r and s are each an integer of 0 to 5; and p + q, and r + s are each in the range of 0 to 5.), which is a novel and efficient catalyst for manufacturing various useful compounds.
Polylithiumorganic compounds. Part 29: C,C Bond cleavage of phenyl substituted and strained carbocycles using lithium metal
Maercker, Adalbert,Oeffner, Kristian S.,Girreser, Ulrich
, p. 8245 - 8256 (2007/10/03)
The reaction of phenyl substituted cyclopropanes phenylcyclopropane and 1,1-diphenylcyclopropane, phenyl substituted bicyclobutanes 1- phenylbicyclobutane, 1-methyl-3-phenylbicyclobutane, 1-methyl-2,2- diphenylbicyclobutane, as well as phenyl substituted spiropentanes phenylspiropentane and 1,1-diphenylspiropentane with lithium metal or lithium di-t-butylbiphenyl (LiDBB) was investigated. Under suitable reaction conditions and choice of solvent in all cases cleavage of the single bond next to the activating phenyl group was observed. The dilithiumorganic compounds thus obtained are sufficiently stable and can be trapped with electrophiles. Lithium hydride elimination is observed as follow-up reaction only in a few cases. The corresponding anions of the strained ring systems 1-lithio-2,2- diphenylcyclopropane, 1-lithio-3-phenylbicyclobutane, 1-lithio-3-methyl-2,2- diphenylbicyclobutane, and 1-lithio-4-phenylspiropentane, which can be obtained by lithium bromine exchange or by metalation of the unsubstituted carbocycle, do not show any cleavage upon reaction with lithium metal. The reaction of phenyl substituted cyclopropanes, bicyclobutanes as well as spiropentanes with lithium metal with formation of highly reactive dilithiumorganic compounds was investigated. In all cases cleavage of the bond next to the phenyl substituent(s) was observed.
Mechanism of Organocalcium Reagent Formation.
Walborsky, H. M.,Hamdouchi, C.
, p. 1187 - 1193 (2007/10/02)
The stereochemistry of the reaction of (S)-(+)-1-bromo- and (S)-(+)-1-chloro-1-methyl-2,2-diphenylcyclopropane and (S)-(+)-1-bromo-1-(methoxymethyl)-2,2-diphenylcyclopropane with calcium-aromatic complexes is reported as is its reaction with a radical clo
