274681-83-3

Upstream product

• 274681-81-1 isopropyl (2R,3S)-3-(acetylamino)-2-(methanesulfonyloxy)-3-phenylpropionate 
• 60512-85-8 (E)-isopropyl cinnamate 
• 7780-06-5 isopropyl cinnamate 
• 342411-01-2 isopropyl (2S,3S)-3-(acetylamino)-2-hydroxy-3-phenylpropionate 
• 195624-97-6 (2R,3S)-3-acetylamino-2-hydroxy-3-phenylpropanoic acid isopropyl ester 

Downstream Products

• 274681-94-6 methyl (2S,3S)-2-amino-3-[(tert-butoxycarbonyl)amino]-3-phenylpropanoate 
• 274681-84-4 isopropyl (2S,3S)-3-(acetylamino)-2-azido-3-phenylpropionate 

Relevant academic research and scientific papers

Efficient asymmetric synthesis of 2,3-diamino-3-phenylpropanoic acid derivatives

An efficient, stereoselective synthesis of selectively-protected anti and syn, methyl 2-amino-3-(Boc-amino)-3-phenylpropanoate is described. Preparation of syn β-acetylamino-α-hydroxy ester was from isopropyl cinnamate via an acetamide-based Sharpless ami

Efficient syntheses and ring-opening reactions of trans- and cis-Oxazoline-5-carboxylates

cis- and trans-Oxazoline-5-carboxylates were synthesized effeciently from isopropyl trans-cinnamate utilizing the sharpless AA reaction. trans-Oxazoline was much more reactive than the cis-isomer toward ring opening reactions. From ab initio molecular calculation, the cis-isomer was predicted to be less reactive than the trans-isomer by 2.7 kcal/mol. Both syn and anti acetylthio ester and anti diamino ester were synthesized from these cis- and trans- oxazoline-5-carboxylates.