27470-51-5

Basic information

• Product Name: 4-BUTYL-4-[HYDROXYMETHYL]-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE HYDROGEN SUCCINATE [ESTER]
• Synonyms: 4-BUTYL-4-[HYDROXYMETHYL]-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE HYDROGEN SUCCINATE [ESTER];SUXIBUZONE;4-butyl-4-(beta-carboxypropionyl-oxymethyl)-1,2-diphenyl-3,5-pyrazolidinedio;4-butyl-4-hydroxymethyl-1,2-diphenyl-3,5-pyrazolidinedionehydrogensuccinate;ae-17;alfide;butanedioicacid,mono((4-butyl-3,5-dioxo-1,2-diphenyl-4-pyrazolidinyl)methyl;flogos
• CAS NO: 27470-51-5
• Molecular Formula: C₂₄H₂₆N₂O₆
• Molecular Weight: 438.47
• EINECS: 248-477-6
• Product Categories: DANILON
• Mol File: 27470-51-5.mol
• Article Data: 0

Chemical Properties

• Melting Point: 126-127°
• Boiling Point: 550.33°C (rough estimate)
• Flash Point: 310.7°C
• Appearance: /
• Density: 1.2847 (rough estimate)
• Vapor Pressure: 9.05E-15mmHg at 25°C
• Refractive Index: 1.6300 (estimate)
• Storage Temp.: 2-8°C
• Solubility: Practically insoluble in water, freely soluble in acetone, soluble in ethanol (96 per cent), practically insoluble in cyclohexane.
• PKA: 4.33±0.17(Predicted)
• CAS DataBase Reference: 4-BUTYL-4-[HYDROXYMETHYL]-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE HYDROGEN SUCCINATE [ESTER](CAS DataBase Reference)
• NIST Chemistry Reference: 4-BUTYL-4-[HYDROXYMETHYL]-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE HYDROGEN SUCCINATE [ESTER](27470-51-5)
• EPA Substance Registry System: 4-BUTYL-4-[HYDROXYMETHYL]-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE HYDROGEN SUCCINATE [ESTER](27470-51-5)

Safety Data

• Hazard Codes: Xn
• Statements: 20/21/22
• Safety Statements: 36
• WGK Germany: 3
• RTECS: WM9640000
• Hazardous Substances Data: 27470-51-5(Hazardous Substances Data)

Usage

Chemical Properties

White or almost white, crystalline powder.

Uses

Different sources of media describe the Uses of 27470-51-5 differently. You can refer to the following data:
1. analgesic, antipyretic, antiinflammatory
2. Suxibuzone is a prodrug of the non steroidal anti inflammatory drug phenylbutazone. It is a drug used for joint and muscular pain.

Definition

ChEBI: A pyrazolidine that is phenylbutazone which is substituted by a 3-carboxypropanoylmethyl group at the 4-position. Suxibuzone is a prodrug for phenylbutazone and is commonly used as an anti-inflammatory drug in horses.

Brand name

Calibene;Danalon om;Danilon;Flamilon;Flofos.

World Health Organization (WHO)

Suxibuzone, a pyrazolone derivative with anti-inflammatory, analgesic and antipyretic activity, was introduced in 1974 for the treatment of rheumatic disorders. As it is structurally related to phenylbutazone, it is subjected to rigorously restricted indications by some national regulatory authorities. See WHO comment for phenylbutazone.

Biochem/physiol Actions

A prodrug of phenylbutazone.

InChI:InChI=1/C24H26N2O6/c1-2-3-16-24(17-32-21(29)15-14-20(27)28)22(30)25(18-10-6-4-7-11-18)26(23(24)31)19-12-8-5-9-13-19/h4-13H,2-3,14-17H2,1H3,(H,27,28)