274917-29-2

Basic information

• Product Name: [1-(2-Azido-phenyl)-ethyl]-[1-thiophen-3-yl-meth-(E)-ylidene]-amine
• Synonyms: [1-(2-Azido-phenyl)-ethyl]-[1-thiophen-3-yl-meth-(E)-ylidene]-amine
• CAS NO: 274917-29-2
• Molecular Weight: 256.331
• Mol File: 274917-29-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [1-(2-Azido-phenyl)-ethyl]-[1-thiophen-3-yl-meth-(E)-ylidene]-amine(CAS DataBase Reference)
• NIST Chemistry Reference: [1-(2-Azido-phenyl)-ethyl]-[1-thiophen-3-yl-meth-(E)-ylidene]-amine(274917-29-2)
• EPA Substance Registry System: [1-(2-Azido-phenyl)-ethyl]-[1-thiophen-3-yl-meth-(E)-ylidene]-amine(274917-29-2)

Safety Data

• Hazardous Substances Data: 274917-29-2(Hazardous Substances Data)

Upstream product

• 498-62-4 3-thiophene carboxaldehyde 
• 146954-07-6 1-(o-azidophenyl)ethylamine 

Downstream Products

• 274917-40-7 Diphenylvinylidene-[2-(1-{[1-thiophen-3-yl-meth-(E)-ylidene]-amino}-ethyl)-phenyl]-amine 

Relevant articles and documents

Highly efficient induction of chirality in intramolecular [2 + 2] cycloadditions between ketenimines and imines

Highly stereocontrolled, intramolecular [2 + 2] cycloadditions between ketenimines and imines leading to 1,2-dihydroazeto[2,1-b]quinazolines have been achieved. The source of stereocontrol is a chiral carbon atom adjacent either to the iminic carbon or nitrogen atom. In the first case, the stereocontrol stems from the preference for the axial conformer in the first transition structure. In the second case, the origin of the stereocontrol lies on the two-electron stabilizing interaction between the C-C bond being formed and the σ* orbital corresponding to the polar C-X bond, X being an electronegative atom. These models can be extended to other related systems for predicting the stereochemical outcome in this intramolecular reaction.