274918-52-4Relevant academic research and scientific papers
α-Ketoamides, α-ketoesters and α-diketones as HCV NS3 protease inhibitors
Han, Wei,Hu, Zilun,Jiang, Xiangjun,Decicco, Carl P.
, p. 711 - 713 (2000)
Peptide-based α-ketoamides, α-ketoesters and α-diketones were designed, synthesized and evaluated against HCV NS3 protease. α-Ketoamides have the highest affinity among the three classes, with 8 being the most potent inhibitor with an IC50 of 3
