27501-84-4

Upstream product

• 97754-31-9 N-(4-methoxyphenyl)-3-phenylpropionamide 
• 104-94-9 4-methoxy-aniline 
• 645-45-4 hydrocinnamic acid chloride 
• 696-62-8 para-iodoanisole 
• 3900-89-8 2-Chlorobenzeneboronic acid 
• 79-06-1 2-propenamide 
• 27382-42-9 1-(2-phenoxy-ethyl)-1H-quinolin-2-one 

Downstream Products

• 54197-74-9 1-(4-hydroxyphenyl)-3,4-dihydrocarbostyril 
• 54197-63-6 3-[2-(4-anisidino)phenyl]-4'-chloropropiophenone 

Relevant academic research and scientific papers

NIS-mediated oxidative arene C(sp2)-H amidation toward 3,4-dihydro-2(1H)-quinolinone, phenanthridone, and N-fused spirolactam derivatives

A new radical-mediated intramolecular arene C(sp2)-H amidation of 3-phenylpropanamides or [1,1′-biphenyl]-2-carboxamides was developed to prepare a series of 3,4-dihydro-2(1H)-quinolinone and phenanthridone derivatives in moderate to excellent yields (33-94%). Spirolactams could also be obtained using this protocol.

Multicomponent multicatalyst reactions (MC)2R: One-pot synthesis of 3,4-dihydroquinolinones

A Rh/Pd/Cu catalyst system led to an efficient synthesis of dihydroquinolinones in one-pot, two operations. The reaction features the first triple metal-catalyzed transformations in one reaction vessel, without any intermediate workup. The conjugate-addition/amidation/amidation reaction sequence is highly modular, divergent, and practical.

3-[2-(4-Anisidino)phenyl]-1-phenyl-1-propiophenones and propanols

The invention relates to novel 1-(4-R1 O-phenyl)-2-(4-R2 -phenyl)-6-R3 -1,2,3,4-tetrahydroquinolines having anti-fertility and hypocholesterolemic activities, to their preparation, and to novel intermediates therefor.

Certain 1,2-diphenyl-1,2,3,4-tetrahydroquinoline compounds

The invention relates to novel 1-(4-R1 O-phenyl)-2-(4-R2 -phenyl)-6-R3 -1,2,3,4-tetrahydroquinolines having antifertility and hypocholesterolemic activities, to their preparation, and to novel intermediates therefor.