27512-24-9Relevant articles and documents
HETEROCYCLIC COMPOUND
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Paragraph 1001-1003, (2016/06/28)
The present invention provides an agent for the prophylaxis or treatment of autoimmune diseases (e.g., psoriasis, rheumatoid arthritis, inflammatory bowel disease, Sjogren's syndrome, Behcet's disease, multiple sclerosis, systemic lupus erythematosus etc.) and the like, which has a superior Tyk2 inhibitory action. The present invention relates to a compound represented by the formula wherein each symbol is as defined in the specification, or a salt thereof.
Studies on Heterocyclic Enaminonitriles. IX. Ring Opening of 2-Amino-3-cyano-4,5-dihydrofurans by the Use of Benzoyl(and Acetyl) Chlorides
Yamagata, Kenji,Tomioka, Yukihiko,Yamazaki, Motoyoshi
, p. 590 - 594 (2007/10/02)
The reaction of 2-amino-3-cyano-4,5-dihydrofuran (Ia) with benzoyl(or acetyl) chloride in the presence of sodium hydride and sodium hydrogen carbonate gave 2-benzoyloxy(or acetoxy)ethylmalononitrile (IIa or IIIa).Similarly, 2-amino-3-cyano-5-methyl-4,5-di
Heterocyclic β-Enamino Esters, 38 - Comparative Investigations on Heterocyclic β-Enamino Nitriles. Synthesis of Heterocondensed Pyrimidines
Wamhoff, Heinrich,Thiemig, Heinz-Albrecht
, p. 4473 - 4485 (2007/10/02)
β-Enamino nitriles of the furan- (1a - e), thiophene- (2), and pyrrole series (3) are obtained from malonodinitrile and oxiranes, thiirane, and N-tosylaziridine in the presence of bases; depending on the reaction conditions in the latter case (1:2)- (pyrr