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Ethychlozate is a chlorinated hydrocarbon compound primarily utilized as a herbicide in agricultural settings. It is a non-selective herbicide that disrupts the photosynthesis process in target plants, leading to their death. However, due to its environmental persistence and potential harmful effects on non-target organisms, its use has been subject to regulatory restrictions and public concern.
Used in Agricultural Industry:
Ethychlozate is used as a herbicide for controlling grass and weed growth in crops. Its non-selective nature allows it to kill a wide range of plant species, making it effective in managing unwanted vegetation. However, its persistence in the environment and potential risks to aquatic ecosystems and human health have led to a decline in its use, with alternative solutions being sought to minimize environmental impact.

27512-72-7

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27512-72-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 27512-72-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,5,1 and 2 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 27512-72:
(7*2)+(6*7)+(5*5)+(4*1)+(3*2)+(2*7)+(1*2)=107
107 % 10 = 7
So 27512-72-7 is a valid CAS Registry Number.
InChI:InChI=1/C11H11ClN2O2/c1-2-16-11(15)6-10-8-5-7(12)3-4-9(8)13-14-10/h3-5H,2,6H2,1H3,(H,13,14)

27512-72-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name ethychlozate

1.2 Other means of identification

Product number -
Other names (5-chloro-1(2)H-indazol-3-yl)-acetic acid ethyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:27512-72-7 SDS

27512-72-7Downstream Products

27512-72-7Relevant academic research and scientific papers

Discovery of substituted indole derivatives as allosteric inhibitors of m6A-RNA methyltransferase, METTL3-14 complex

Jin, Mi Sun,Kim, Subin,Kim, Yong-Chul,Lee, Je-Heon

, (2022/01/20)

m6A RNA methyltransferase (METTL3-14) catalyzes the methylation of adenosine in mRNA and plays important roles in mRNA functions, and it has been implicated in the progression of multiple cancers, including acute myeloid leukemia (AML). In this study, we describe the discovery of the first allosteric inhibitor of the METTL3-14 complex based on structure–activity relationship (SAR) and optimization studies of the hit compound, 4-[2-[5-chloro-1-(diphenylmethyl)-2-methyl-1H-indol-3-yl]-ethoxy]benzoic acid (CDIBA). Compound 43n was optimized throughout the modifications of 4 different regions of the structure, and it displayed potent enzyme inhibitory activity of the METTL3-14 complex (IC50?=?2.81 μM) and an antiproliferative effect in the AML cell lines by suppressing the m6A level of mRNA. The inhibition mechanism and binding mode of 43n were based on the interaction of the reversible and noncompetitive inhibitory profile at the allosteric site along with selectivity for the METTL3-14 complex relative to each subunit enzyme or truncated complex enzyme.

Patch preparations for treating plants

-

, (2008/06/13)

The following invention introduces a patch preparation for treating plants, whereas the patch preparations comprise a chemical layer composed of at least one agrochemically active compound, at least one adhesive and optionally, one or more additives. The components are dispersed in a matrix state on a substrate which are then introduced on the roots of the plant to be treated.

Orally Active Aldose Reductase Inhibitors: Indazoleacetic, Oxopyridazineacetic, and Oxopyridopyridazineacetic Acid Derivatives

Mylari, Banavara L.,Zembrowski, William J.,Beyer, Thomas A.,Aldinger, Charles E.,Siegel, Todd W.

, p. 2155 - 2162 (2007/10/02)

Benzothiazole side chains featured in zopolrestat (1a) and its congeners were incorporated into oxophthalazineacetic acid replacements, including indazole, pyridazinone, and pyridopyridazinone with a pendant acetic acid moiety.Potent aldose reductase inhi

Method for thinning young fruits and blossoms and agent therefor

-

, (2008/06/13)

Method for thinning young fruits and blossoms by applying to fruit trees, particularly citrus fruit trees an indazole compound of the formula: STR1 wherein R is hydrogen or a lower alkyl having 1 to 4 carbon atoms, and X is a halogen, or the salt thereof, and a thinning agent containing as the active ingredient the indazole compound as mentioned above.

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