275355-92-5Relevant articles and documents
Studies in Marine Polypropionate Synthesis: Total Synthesis of (-)-Baconipyrone C
Paterson, Ian,Chen, David Yu-Kai,Acena, Jose Luis,Franklin, Alison S.
, p. 1513 - 1516 (2000)
(Equation Presented) An asymmetric total synthesis of the unusual siphonariid metabolite, (-)-baconipyrone C (3), is described. Key steps included a tin(II)-mediated aldol coupling for the preparation of the carboxylic acid 17 and two different boron-mediated aldol additions leading to alcohol 8. Ester formation using modified Yamaguchi conditions gave 24, leading on PMB deprotection to (-)-baconipyrone C.