275355-95-8

Upstream product

• 275356-05-3 Acetic acid (1S,2R,3R,4R)-1-[(S)-1-(6-ethyl-3,5-dimethyl-4-oxo-4H-pyran-2-yl)-ethyl]-3-(4-methoxy-benzyloxy)-2,4-dimethyl-5-triisopropylsilanyloxy-pentyl ester 
• 275355-98-1 Acetic acid (1S,2R,3R,4R)-1-[(S)-1-(6-ethyl-3,5-dimethyl-4-oxo-4H-pyran-2-yl)-ethyl]-3-hydroxy-2,4-dimethyl-5-triisopropylsilanyloxy-pentyl ester 
• 275356-06-4 Acetic acid (1S,2R,3R,4R)-1-[(S)-1-(6-ethyl-3,5-dimethyl-4-oxo-4H-pyran-2-yl)-ethyl]-5-hydroxy-3-(4-methoxy-benzyloxy)-2,4-dimethyl-pentyl ester 
• 275355-97-0 2-Ethyl-6-((1S,2R,3S,5R)-2-hydroxy-1,3,5-trimethyl-4-oxo-6-triisopropylsilanyloxy-hexyl)-3,5-dimethyl-pyran-4-one 
• 143627-33-2 (R)-2-Methyl-1-triisopropylsilanyloxy-pentan-3-one 
• 89238-99-3 O-(4-methoxybenzyl)-trichloroacetimidate 
• 275355-99-2 2-((2S,3S,4S,5R,6R)-3,7-dihydroxy-5-((4-methoxybenzyl)oxy)-4,6-dimethylheptan-2-yl)-6-ethyl-3,5-dimethyl-4H-pyran-4-one 

Downstream Products

• 275356-01-9 p-methoxybenzyl baconipyrone C 

Relevant academic research and scientific papers

Total synthesis of (-)-baconipyrone C

A highly stereoselective asymmetric total synthesis of marine polypropionate (-)-baconipyrone C has been achieved. Utilization of desymmetrization technique to create five stereogenic centres, Sharpless epoxidation, Gilman's reaction and resolution of met

Studies in Marine Polypropionate Synthesis: Total Synthesis of (-)-Baconipyrone C

(Equation Presented) An asymmetric total synthesis of the unusual siphonariid metabolite, (-)-baconipyrone C (3), is described. Key steps included a tin(II)-mediated aldol coupling for the preparation of the carboxylic acid 17 and two different boron-mediated aldol additions leading to alcohol 8. Ester formation using modified Yamaguchi conditions gave 24, leading on PMB deprotection to (-)-baconipyrone C.