2755-00-2Relevant academic research and scientific papers
PHOTOCHEMICAL SYNTHESIS OF APORPHINES: (+/-)-THALIPORPHINE, (+/-)-N-METHYLLAUROTETANINE AND (+/-)-ISOBOLDINE.
Gupta, Sandeep,Bhakuni, Dewan S.
, p. 2251 - 2258 (2007/10/02)
Aporphines, (+/-)-thaliporphine (1), (+/-)-N-methyllaurotetaline (2), and (+/-)-isoboldine (3) were synthesised using photochemical cyclization as the key step.
ALKALOIDS OF Glaucium fimbrilligerum. II
Karimova, S. U.,Israilov, I. A.,Vezhnik, F.,Yunusov, M. S.,Slavik, Yu.,Yunusov, S. Yu.
, p. 464 - 467 (2007/10/02)
The alkaloids of the epigeal part and roots of the plant Glaucium fimbrilligerum have been studied.A total of 18 alkaloids has been isolated, of which epiglaufidine proved to be new, and its structure has been established.Columbamine has been isolated from the genus Glaucium for the first time, and magnoflorine and stilopine α-hydroxymethylate from this species of plant for the first time.
THE DEMETHYLATION OF APORPHINES WITH SULFURIC ACID
Castedo, Luis,Lera, Angel Rodriguez de,Saa, Jose M.,Suau, Rafael,Villaverde, Carmen
, p. 1135 - 1138 (2007/10/02)
Sulfuric acid at room temperature has been found a useful reagent for interconverting aporphine alkaloids by selective O-demethylation.This was controlled by electronic or steric effects.
Synthesis of hernandaline
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, (2008/06/13)
There is disclosed a novel and improved method of synthesizing aporphines utilizing the Pschorr cyclization of 1-(2'-aminobenzyl)-7 hydroxy-1,2,3,4-tetrahydroisoquinolines in place of the corresponding 7-methoxy compounds. In the novel process of the present invention the amino group is diazotized and cyclized in the presence of copper powder.
