27559-50-8

Basic information

• Product Name: N-phenyl-3-(4-hydroxyphenyl)propenamide
• Synonyms: N-phenyl-3-(4-hydroxyphenyl)propenamide
• CAS NO: 27559-50-8
• Molecular Weight: 239.274
• Mol File: 27559-50-8.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: N-phenyl-3-(4-hydroxyphenyl)propenamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-phenyl-3-(4-hydroxyphenyl)propenamide(27559-50-8)
• EPA Substance Registry System: N-phenyl-3-(4-hydroxyphenyl)propenamide(27559-50-8)

Safety Data

• Hazardous Substances Data: 27559-50-8(Hazardous Substances Data)

Upstream product

• 110-89-4 piperidine 
• 110-86-1 pyridine 
• 15580-32-2 malonanilic acid 
• 123-08-0 4-hydroxy-benzaldehyde 
• 104315-07-3 (E)-ethyl 3-(4-(benzyloxy)phenyl)acrylate 
• 6272-45-3 (E)-4-benzyloxycinnamic acid 
• 103-84-4 Acetanilid 
• 7400-08-0 p-Coumaric Acid 
• 62-53-3 aniline 
• 7400-08-0 para-coumaric acid 

Downstream Products

• 1139588-39-8 4-[3-(phenylamino)-4,5-dihydroisoxazol-5-yl]phenol 
• 203179-61-7 4-(tetra-O-acetyl-β-D-glucopyranosyloxy)-trans-cinnamaldehyde 
• 2538-87-6 trans-p-hydroxycinnamaldehyde 

Relevant articles and documents

Investigation of the effect of the NH···OC hydrogen bond from Cys69 to PYP chromophore using novel active-center model compound

A PYP active-center model compound containing a hydrogen bond to the conjugated carbonyl oxygen was synthesized and its effect on the electronic properties of the chromophore were investigated. The intramolecular hydrogen bond induces significant change i

Phenolic Acids from Sugarcane Bagasse Lignin: Qualitative and Quantitative Determination, Isolation, Derivatization, and Biological Activity Evaluation

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Synthesis and structure-activity relationship analysis of caffeic acid amides as selective matrix metalloproteinase inhibitors

Four series of acid amides were synthesized, and through measurement using a fluorogenic substrate assay with human recombinant MMP-1, MMP-2 and MMP-9, compound 3f showed considerable inhibitory activities against MMP-2, MMP-9 and the best selectivity over MMP-1. Preliminary structure-activity relationship analysis indicated that caffeic acid amides with electron-donating groups at para-position of amino phenyl group showed better inhibitory activities and selectivity than those with electron-withdrawing groups, and the presence of adjacent dihydroxy in the caffeoyl group was very important for the MMP-2 and MMP-9 inhibitory activities.