27581-00-6 Usage
Drug Class
Beta-blockers
Medical Uses
High blood pressure
Angina
Irregular heart rhythms
Migraines
Anxiety
Stage fright
Social anxiety disorder
Mechanism of Action
Blocks the action of natural substances like adrenaline, affecting the heart and blood vessels
Effects on the Body
Lowers blood pressure
Reduces strain on the heart
Improves heart's ability to pump blood
Forms Available
Tablet, extended-release capsule, and solution
Side Effects
Dizziness, tiredness, nausea
Contraindications
Not for use in people with certain heart conditions or allergies to the drug
Check Digit Verification of cas no
The CAS Registry Mumber 27581-00-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,5,8 and 1 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 27581-00:
(7*2)+(6*7)+(5*5)+(4*8)+(3*1)+(2*0)+(1*0)=116
116 % 10 = 6
So 27581-00-6 is a valid CAS Registry Number.
InChI:InChI=1/C16H23NO2/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16/h3-5,7,9,12,14,17-18H,6,8,10-11H2,1-2H3
27581-00-6Relevant academic research and scientific papers
Nondepressant β-adrenergic blocking agents. I Substituted 3-amino-1-(5, 6, 7, 8-tetrahydro-1-naphthoxy)-2-propanols
Condon,Cimarusti,Fox,Narayanan,Reid,Sundeen,Hauck
, p. 913 - 922 (2007/10/06)
A series of 3-amino-1-(5,6,7,8-tetrahydronaphthoxy)-2-propanols was synthesized and investigated for β-adrenergic blocking activity and direct myocardial depressant action. The cis- and trans-diols 12-15 were found to retain the β-blocking potency of propranolol but to lack its myocardial depressant action. Compound 15 (nadolol) is currently undergoing extensive clinical evaluation as a potential antianginal, antiarrhythmic, and antihypertensive agent.
